MicrobeWorld App

appsquarebannerad200x200

Join MicrobeWorld

Subscribe via Email

subscribe

Microbes After Hours

MW-Site-Banner-200x200

Click for more "Microbes After Hours" videos

Featured Image

Featured Video

Crowdsourced Microbes Heading to Station

Supporters

ASM House 200X200

Detecting disease with a little TLC

A simple, low cost method to detect toxins from the organism causing the wasting disease Buruli ulcer has been developed by US scientists.

Buruli ulcer is a wasting disease caused by organisms called Mycobacterium Ulcerans, which are in the same group as the organisms causing leprosy and tuberculosis. Early diagnosis and treatment are vital as delayed treatment may cause irreversible deformity, long-term functional disability such as restriction of joint movement, extensive skin lesions and sometimes life-threatening secondary infections.

Polymerase chain reaction of M.ulcerans DNA is commonly used to detect the infection, but is expensive and difficult to maintain reliably say Yoshito Kishi and Thomas Spangenberg from Harvard University, Cambridge. They have created a simple but highly sensitive fluorescent detector for mycolactones, the toxins secreted by M. Ulcerans and distributed within the infected tissue.
 
 

Comments (0)

Collections (0)

 

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use