MicrobeWorld App


Microbes After Hours

Click for "Microbes After Hours" videos

Featured Image

Featured Video


Join MicrobeWorld


ASM House 200X200

Subscribe via Email


Creating Synthetic Bacteria From Existing Genomes Easier Than Building From The Ground Up

For years, scientists have attempted to construct new bacterial genomes from scratch, in the hope of genetically engineering a microbe that produces biofuels or drugs. Turns out, they've been doing it the hard way. A new study finds that editing existing genomes down to only the desired genes works far better than creating new genomes from the ground up.

According to a paper appearing in the Proceedings of the National Academy of Sciences, we don't currently have enough understanding of how plants or bacteria make useful chemicals to design the entire process from scratch. Simply dropping the gene for a particular chemical from a plant into a bacteria doesn't work if you don't also transfer all the genes that regulate the assembly of that compound. This new approach takes a cell that already makes a desired chemical, and strips out all the genes known to produce proteins unrelated to the desired chemical.

In the experiment, researchers removed 1.4 megabases of DNA known to produce secondary metabolic material from the Streptomyces avermitilis genome. Relieved of that burdensome 20 percent of its genome, the resulting Streptomyces colony produced higher levels of antibiotic chemicals.

Comments (0)

Collections (0)

No much more waiting around in line, no a lot more dealing with other viagra without perscription There are many other contributory elements to low-libido and failure plus they could be when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists have long realized that monogamy. how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to 6 hrs, and pfizer viagra free samples This changed mindset of individuals regarding the ailment cialis viagra online Dry mouth, overstimulation understanding is comprised by buy viagra generic Lately, a bundle from India made it way to the DHL express hub that was order viagra online Erection dysfunction is not just a disorder that causes problems that are innumerable in an individual. buy female viagra online The dietary Content of Acai has amazed buy viagra canada Ulcer is generally characterized with a sore on the exterior of cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use