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Glaxo's swine flu shot may give kids fever

The European Medicines Agency warns that young children given GlaxoSmithKline's swine flu shot may get a fever after their second dose.

In a statement issued Friday, the European drug regulator said data from GlaxoSmithKline PLC showed a higher number of children aged six months to 3 years had a fever after their second dose of the Pandemrix vaccine, compared with the first. Kids were also more likely to have side effects like muscle pain, drowsiness, and irritability.

The European regulator recommends children get two doses of swine flu vaccine, though Glaxo says one dose is enough.

Glaxo's vaccine contains an adjuvant, a chemical compound to boost the immune response. It is sold across Europe and Canada.

Another formulation of Glaxo's vaccine, without the adjuvant, is available in the U.S. Vaccines with adjuvants usually cause more side effects. No flu vaccines with adjuvants are licensed in the U.S.

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