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Nanoparticles used in common household items cause genetic damage in mice

Titanium dioxide nanoparticles, found in everything from cosmetics and sunscreen to paint and vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA's Jonsson Comprehensive Cancer Center.

Titanium dioxide (TiO2) nanoparticles induced single- and double-strand DNA breaks and caused chromosomal damage, as well as inflammation, all of which increase the risk of cancer.

The UCLA study is the first to show that the nanoparticles had such an effect, said senior study author Robert Schiestl, UCLA professor of pathology, radiation oncology and environmental health sciences and a Jonsson Cancer Center scientist.

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