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Major Advance In Human Antibody Therapy Against Deadly Nipah Virus

A collaborative research team from the Uniformed Services University of the Health Sciences (USU), Australian Animal Health Laboratory and National Cancer Institute, a component of the National Institutes of Health, reports a major step forward in the development of an effective therapy against two deadly viruses, Nipah virus and the related Hendra virus.

Nipah and Hendra viruses are found in Pteropid fruit bats (flying foxes) and are characterized by their recent emergence as agents capable of causing illness and death in domestic animals and humans.

In experiments carried out in ferrets at the Australian Animal Health Laboratory in Geelong, Victoria, Australia, where there is a high-level safety and security facility for working with live Nipah and Hendra viruses, the team of researchers demonstrated that giving an anti-virus human monoclonal antibody therapy after exposure to Nipah virus protected the animals from disease.
 
 

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