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Global Transcriptional Response of Acinetobacter baumannii to Light Exposure

While detection and reaction to light sources is a well-known process in environmental organisms exposed to diurnal light cycling, light detection also affects the biological processes of human pathogens. The human pathogen Acinetobacter baumannii, a microbe associated with hospital-acquired infections, responds to light to become less susceptible to specific antibiotics. A new Journal of Bacteriology study explores some of the additional physiological changes that may explain the A. baumannii light response. The authors find that “light modulates global features of A. baumannii lifestyle,” including effects on metabolic pathway expression levels, antioxidant enzyme levels, antibiotic resistance and pathogenicity.
 
 

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