MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

Spillover-Banner
Click for "Microbes After Hours" videos

Featured Image

Featured Video

MWV102featured

New from ASM Press

MWSquare200x200

Join MicrobeWorld

Supporters

ASM House 200X200

Subscribe via Email

subscribe

Treating gum disease with oral microbiota transplants

Image
According to the American Academy of Periodontology, about half of American adults have periodontal disease, which affects gum tissues and the bones supporting the teeth. Apparently, the prevalence of periodontal disease increases with age, with the highest prevalence for those that smoke, those living below the federal poverty level, and those with less than a high school education. Although regular maintenance can minimize periodontal disease, there is no cure. Our recent study presents a path forward to a new alternative: oral microbial transplant, which is inspired by the success of fecal transplants. The path involved finding a way to discriminate healthy oral microbiomes from unhealthy ones and finding a way to kill the bacteria in the diseased mouths to enable the healthy transplanted oral microbes to thrive and persist in the disinfected mouth of the recipient. We successfully identified the microbial signatures of subjects with periodontitis and oral health and we discovered that dilute bleach is an effective way to disinfect a recipient mouth of unhealthy microorganisms. We also found that Vitamin C is an effective way to neutralize the effects of diluted bleach prior to introduction of the healthy oral microbiota to the recipient’s mouth. With this new information, we designed an experimental plan to test the utility of oral microbiota transplants in animals. We have applied for research funding to move forward.

The article describing this research was published in the journal BMC Oral Health 15:125 on October 16, 2015. The research article is entitled: “Towards microbiome transplant as a therapy for periodontitis: an exploratory study of periodontitis microbial signature contrasted by oral health, caries and edentulism”.
 
 

Comments (0)

Collections (0)

 
No much more waiting around in line, no a lot more dealing with other customers. Purchasing requires. viagra without perscription There are many other contributory elements to low-libido and failure plus when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists have long realized that monogamy. how to get viagra samples free Kamagra Gel allows the dude to handle pfizer viagra free samples This changed mindset of individuals regarding the ailment is however not a cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL order viagra online Erection dysfunction is not just a disorder that causes problems buy female viagra online The dietary Content of Acai has amazed several of the whole buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use