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New Study Suggests an Unidentified Source as Cause of Residual Viremia in HIV-1 Patients on HAART

A new study suggests that an unidentified cellular source may be responsible for residual viremia in HIV-1 patients on highly active antiretroviral therapy (HAART). This discovery disputes previous theories that attributed residual viremia to latent proviruses in resting CD4+ T cells and could significantly impact eradication efforts. The researchers from The Johns Hopkins University School of Medicine, Baltimore, Maryland; The University of Texas, Austin; and the Howard Hughes Medical Institute, Baltimore, Maryland report their findings in the September 2009 issue of the Journal of Virology.

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