Scientists may be able to entomb the malaria parasite in a prison of its own making, researchers report. As it invades a red blood cell, the malaria parasite takes part of the host cell's membrane to build a protective compartment. The parasite then starts a series of major renovations that transform the red blood cell into a suitable home. But the new research reveals the proteins that make these renovations must pass through a single pore in the parasite's compartment to get into the red blood cell. When the scientists disrupted passage through that pore in cell cultures, the parasite stopped growing and died.
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