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Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

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Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces pombe has been used to brew beer in Africa, whereas its close relative S. kombucha is a component of kombucha tea commonly found in health-food stores.

A team of researchers led by Dr. Sarah Zanders of the Basic Sciences Division at Fred Hutch, has uncovered why hybrids between these yeasts (commonly referred to as fission yeasts) are almost completely sterile despite being 99.5 percent identical at the DNA level.

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