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HIV Can Cut and Paste in the Human Genome

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Aarhus University has developed a technology that uses the HIV virus as a tool in the fight against hereditary diseases - and in the long term, against HIV infection as well. The technology repairs the genome in a new and safer manner.

For the first time researchers have succeeded in altering HIV virus particles so that they can simultaneously, as it were, ‘cut and paste’ in our genome via biological processes. Developed at the Department of Biomedicine at Aarhus University, the technology makes it possible to repair genomes in a new way. It also offers good perspectives for individual treatment of both hereditary diseases and certain viral infections:

"Now we can simultaneously cut out the part of the genome that is broken in sick cells, and patch the gap that arises in the genetic information which we have removed from the genome. The new aspect here is that we can bring the scissors and the patch together in the HIV particles in a fashion that no one else has done before," says associate professor in genetics Jacob Giehm Mikkelsen from Aarhus University.

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