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Lonely Bacteria Mutate Faster

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Bacteria that have no friends don’t get sad; they get weird. When E. coli cells sense fewer other bacteria around them, their DNA starts to mutate at a faster rate. That’s bad news for humans and our antibiotics. But if we can make bacteria feel less alone, we might be able to slow down their destructive rampages.

“Personally, I find it pretty surprising that this hasn’t been pinned down before,” says Christopher Knight, a lecturer in the University of Manchester’s Faculty of Life Sciences. The discovery didn’t take any kind of high-tech tests. Lead author Rok Krasovec, a member of Knight’s research group, simply grew E. coli bacteria in varying amounts of food. Cells with more food went through a greater number of generations every day, creating denser populations; those with less food multiplied more slowly.

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