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Nutrient-absorbing surface’s assembly revealed: study

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Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in the journal Cell, reveal a role for adhesion molecules in brush border assembly and increase our understanding of intestinal pathologies associated with inherited and infectious diseases. Pathogens that destroy the intestinal brush border cause diarrhea and death — a particular problem in communities that do not have safe water supplies.

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