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The malaria pathogen’s cellular skeleton under a super-microscope

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The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different versions of this protein in the parasite in high detail. Their results, published in the scientific journal “PLOS Pathogens”, may in the future contribute to the development of tailor-made drugs against malaria–a disease that causes more than half a million deaths per year.

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