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Mycobacteriophages: Windows into Tuberculosis

Mycobacteriophages are viruses that infect mycobacterial hosts, such as Mycobacterium tuberculosis and Mycobacterium smegmatis. Mycobacteriophages display a remarkable genetic diversity. About 30 distinct types (called clusters, or singletons if they have no relatives) that share little or no nucleotide sequence similarity have been identified. The increased prevalence of antibiotic resistance in bacterial pathogens has spurred renewed interest in the therapeutic use of bacteriophages.

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