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Mix Of Gut Microbes May Play Role In Crohn's Disease

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More than a million Americans suffer from Crohn's, which seems to start when an overreactive immune system causes abdominal pain, diarrhea, bleeding, weight loss and other symptoms. Many patients have to take powerful steroids (which can have serious side effects), and some have parts of the digestive tract surgically removed. Mounting evidence has suggested that microbes living in the gut might contribute to the problem. So Xavier and his colleagues compared the species of bacteria in more than 447 Crohn's patients to the mix of microbes in more than 221 healthy people.

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