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Bacteria Take On Completely New Flat Shape To Fit Through Nanoslits

It appears that bacteria can squeeze through practically anything. In extremely small nanoslits they take on a completely new flat shape. Even in this squashed form they continue to grow and divide at normal speeds. This has been demonstrated by research carried out at TU Delft's Kavli Institute of Nanoscience. The results will be appearing this week in the online edition of the scientific journal Proceedings of the National Academy of Sciences (PNAS) and as the cover article in the September 1 print issue of PNAS.

Using nanofabrication, Delft scientists made minuscule channels, measuring a micrometer or less in width and 50 micrometer in length, on a silicon chip between tiny chambers containing bacteria. Subsequently they studied the behaviour of Escherichia. coli and Bacillus. subtilis bacteria in this artificial environment. The bacteria were genetically modified so that they were fluorescent and could easily be followed using a special microscope.
 
 

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