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Researchers discover a tumor suppressor gene in a very aggressive lung cancer

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The Genes and Cancer Group at the Cancer Epigenetics and Biology Program of the IDIBELL has found that the MAX gene, which encodes a partner of the MYC oncogene, is genetically inactivated in small cell lung cancer. Reconstitution of MAX significantly reduced cell growth in the MAX-deficient cancer cell lines. These findings show that MAX acts as a tumor suppressor gene in one of the more aggressive types of lung cancer.

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