MicrobeWorld App

appsquarebannerad200x200

Join MicrobeWorld

Subscribe via Email

subscribe

Microbes After Hours

shutdown

Click for more "Microbes After Hours" videos

Featured Image

Featured Video

Crowdsourced Microbes Heading to Station

Supporters

ASM House 200X200

New study of human blood fluke parasites identifies drug resistance mutations

An international group of scientists led by Tim Anderson Ph.D., at the Texas Biomedical Research Institute and Philip LoVerde Ph.D., at the University of Texas Health Science Center at San Antonio has identified the mutations that result in drug resistance in a parasite infecting 187 million people in South America, Africa and Asia. The new finding allows detailed understanding of the drugs' mechanism of action and raises prospects of improved therapies.

"This is a major advance," said Claudia Valentim, Ph.D., the primary author of the report, who worked at both institutions. "We were able to identify the critical gene by crossing resistant and sensitive worms in the laboratory and then analyzing the genomes of the progeny. This method is commonly used for fruit flies and other laboratory organisms, but has not previously been possible for schistosome parasites."

Click "source" to read the entire article.
 
 

Comments (0)

Collections (0)

 

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600

Copyright © American Center for Microbiology 2012. All Rights Reserved.