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New method to diagnose sepsis is faster, cheaper

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In managing bloodstream infections, minutes count, and delays in treatment or administering the wrong antibiotic can kill a patient. In mBio today, scientists from bioMérieux, Inc. describe a new method that could cut hours off the time it takes to diagnose blood infections while also eliminating the need for complicated manual processing and expensive equipment. The method combines a selective lysis step in which blood cells in the sample are destroyed, a centrifugation step to collect any bacteria or fungi in the sample, and a fluorescence step that analyzes the particular fingerprint of any pathogens present in the sample. Tests show the method correctly identifies the species of bacteria or fungi in 96.5 % of positive blood culture samples, crucial information for doctors to provide the appropriate drugs for their patients.
 
 

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