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Plasmas attack bacterial cells on several levels

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As they destroy bacteria very efficiently, plasmas constitute an alternative to chemical disinfectants and potentially to antibiotics, as well. How they achieve this effect has been investigated by biologists, plasma physicists and chemists at the Ruhr-Universität (RUB). Cold atmospheric-pressure plasmas attack the prokaryote’s cell envelope, proteins and DNA. “This is too great a challenge for the repair mechanisms and the stress response systems of bacteria,” says Junior Professor Dr Julia Bandow, Head of the Junior Research Group Microbial Antibiotic Research at the RUB. “In order to develop plasmas for specific applications, for example for treating chronic wounds or for root canal disinfection, it is important to understand how they affect cells. Thus, undesirable side effects may be avoided right from the start.” The team reports in the “Journal of the Royal Society Interface”.

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