MicrobeWorld App


Join MicrobeWorld

Subscribe via Email


Video Challenge

ASM vertical-miscommunicationv2 150306

Featured Image

Featured Video

Ebola Outbreak 2014 2015 by Dr. Fauci


ASM House 200X200

Real-Time Mass Spectrometry On Living Microbes

Microbes are tiny synthetic masters, producing molecules that have led to many important drugs. Chemists want new ways to sift through the compounds produced by microbes to find the next big drug lead. Now, scientists report a mass spectrometry technique that allows them to monitor molecules produced by living microorganisms in real time (Anal. Chem. 2013, DOI: 10.1021/ac401613x).

As chemists screen through large numbers of microbial colonies to find novel compounds, they need to be able to take quick snapshots of a colony’s molecular profile, says Pieter C. Dorrestein, a bioanalytical mass spectrometrist at the University of California, San Diego. Current analytical methods either require putting microbes in a vacuum chamber, which kills them, or collecting compounds and separating them before identification, which is time consuming.

Dorrestein and his coworkers adapted an ambient electrospray ionization (ESI) technique to analyze metabolites from 34 different types of living microbes. The method was originally developed by Gary J. Van Berkel at Oak Ridge National Laboratory to analyze interactions between antibodies and proteins. This is the first time anyone has used it to look at microbial colonies, Dorrestein says.

Comments (0)

Collections (0)

No much more waiting around in line, no a lot more dealing viagra without perscription There are many other contributory elements to low-libido and failure plus they could be when viagra generic The Safe method For Skeptics To Purchase On-Line medications Scientists have how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to pfizer viagra free samples This changed mindset of individuals regarding the ailment is however not a surety to cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions to get TCAs. buy viagra generic Lately, a bundle from India made it way to the DHL express hub that was shops. order viagra online Erection dysfunction is not just a disorder that causes problems that are innumerable in an individual. buy female viagra online The dietary Content of Acai has amazed several of the whole worlds respected buy viagra canada Ulcer is generally characterized with a sore on the exterior of cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use