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Researchers describe the full genome structure for HIV-1

In a paper published in Nature, a research team from the University of North Carolina described the full genome structure of HIV-1 for the first time.

"The researchers used a high-throughput method called "selective 2'-hydroxyl acylation analyzed by primer extension" (SHAPE) to glean structural information for nearly every nucleotide in the HIV-1 genome. The team also started identifying structural patterns that may offer clues about the virus' function and potential vulnerabilities — including an apparent link between RNA and protein structure."
 
 

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