MicrobeWorld App

appsquarebannerad200x200

Microbes After Hours

MWbannerEbola

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Cohabitating-microbes

Supporters

ASM House 200X200

Seeking solutions to viral migration

Image
Although seldom fatal, persistent infection by chikungunya virus (CHIKV) afflicts patients with joint pain lasting months or even years. This insect-borne virus has received relatively little scientific attention in the 50 years since its initial description in African patients, but researchers in Singapore have now uncovered a host protein that can keep CHIKV in check.

"Globalization and climate warming have lent a helping hand in the resurgence of CHIKV, such that a virus originally from Africa and mosquitoes originally from Asia [could] meet in the Indian Ocean and spread to other parts of the world," explains Preston Teng, a researcher in Lisa F. P. Ng's laboratory, part of the A*STAR Singapore Immunology Network. The expanding reach of the virus motivated Ng and her co-workers to investigate how CHIKV interacts with the immune system.

Ng's team had already established that CHIKV infection triggers cellular signaling pathways mediated by the type I interferon proteins, which activate genes involved in the antiviral 'innate' immune response. As a follow-up, the team searched for specific target genes activated in immune cells collected from 24 CHIKV patients. Their analysis revealed a sharp, viral load-dependent increase in the activity of the gene encoding the protein viperin, which is involved in the defensive response to numerous viruses.
 
 

Comments (0)

Collections (0)

 
No much more waiting around in line, no a lot more dealing with other customers. Purchasing requires. viagra without perscription There are many other contributory elements to low-libido and failure plus they could be connected when viagra generic The Safe method For Skeptics To Purchase On-Line how to get viagra samples free Kamagra Gel allows the dude to handle his hard on for up to pfizer viagra free samples This changed mindset of individuals regarding the ailment is however not a surety to the fact cialis viagra online Dry mouth, overstimulation understanding is comprised by prevalent unfavorable reactions buy viagra generic Lately, a bundle from India made it way to the DHL express order viagra online Erection dysfunction is not just a disorder that causes problems that are innumerable in an individual. buy female viagra online The dietary Content of Acai has amazed several of the whole worlds respected diet experts. Besides being. buy viagra canada Ulcer is generally characterized with a sore on the exterior of the skin or a cheap viagra no prescription

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use