Malaria is one of the most important infectious diseases in the developing world, with the absence of a vaccine and the development of parasite resistance to commonly used antimalarial drugs complicating efforts to fight the deadly disease.
The parasite that causes malaria is Plasmodium, which requires specific human and mosquito tissues to complete its life cycle. The progression and control of this life cycle could be better understood by studying changes of the 3-D structure of the parasite’s genome.
The University of California, Riverside and the University of Washington have received a four-year grant of more than $2 million from the National Institutes of Health to discover this 3-D structure of Plasmodium’s genome during the parasite’s erythrocytic cycle that is responsible for disease in humans.
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