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Study defines level of dengue virus needed for transmission

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Researchers have identified the dose of dengue virus in human blood that is required to infect mosquitoes when they bite. Mosquitoes are essential for transmitting the virus between people, so the findings have important implications for understanding how to slow the spread of the disease.

By defining the threshold for transmission, the research also provides a target that experimental dengue vaccines and drugs must prevent the virus from reaching in order to be successful at preventing the spread of disease during natural infection.

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