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A 'neurosteroid' found to prevent brain injury caused by HIV/AIDS (press release)

New research in The FASEB Journal suggests that a network of steroid molecules found in the brain is disrupted during HIV infection, and treatment with the steroid DHEA-S prevents brain damage.

A team of scientists from Canada, Thailand and Morocco have found that DHEA-S may prevent neurocognitive impairment that affects a significant percentage of AIDS patients. In a report appearing in the February 2013 issue of The FASEB Journal, they describe how a network of steroid molecules found in the brain, termed "neurosteroids," is disrupted during HIV infection leading to brain damage. This suggests that treatment with one of these steroid molecules, called DHEA-S, may offset the disruption caused by the virus to prevent or reduce brain damage.

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