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TWiM 23 Letters

Joe writes:

Hello Vincent and Elio

Your recent discussion of mitochondrial interconnections reminded me of a
paper by Dubey and Ben-Yehuda I saw earlier this year describing
intercellular communication utilizing tiny nanotubes that are EM
visualizable and that can transfer DNA, RNA and protein from bacterium to
bacterium.  These structures are able to connect distinct bacterial species
and can confer transient antimicrobial resistance as well as other
phenotypes from one species to another.  I was completely blown away by this
paper and it forced me to think about all of the things that we still don't
really understand about the bacterial world.  The paper is worth looking at
if only for the beautiful microscopy work and elegant experimental details.
I wonder if you'd care to comment on whether this type of mechanism could
explain the origins of the mitochondrial interconnections that you were
discussing on TWIM 21?

I really enjoy the program as it lets me keep up on interesting developments
in areas Ativan Dosage of microbiology outside of my own field.  All the best,

Joe McPhee
----------------------------------------------------------------------------
Joseph McPhee Ph.D.
Michael G. DeGroote Postdoctoral Fellow
Coombes Laboratory
McMaster University

Don writes:

All hail the microbiologists extrordinarie. I look forward to your discussion of the paper on the use of copper to discourage bacterial growth, as you discussed in an early twim.  I was able to convince myself using a copper plated car battery and CuSo4. ie "root killer" and chicken broth for a medium and clarity as an end point. I have since switched to brass, as  it  is more durable, and already "out there" in the market, avoiding the medical vendor or defense contractor  monetary gouge, but the results have not been quite so clear cut. Could you speculate or theorize why this might be so, for an alloy of copper and zinc, vs Cu alone? I delight in your podcasts, and have filled out your questionnaire/survey. Best to you all and please keep going.

DW,MD
 

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