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TWiV 420: Orthogonal vectors

The TWiV gurus describe how to use an orthogonal translation system to produce infectious but replication-incompetent influenza vaccines.


Hosts: Vincent Racaniello Read More

An ancient killer: Ancestral malarial organisms traced to age of dinosaurs

CORVALLIS, Ore. - A new analysis of the prehistoric origin of malaria suggests that it evolved in insects at least 100 million years ago, and the first vertebrate hosts of this disease were probably reptiles, which at that time would have included the dinosaurs. Read More

Cloning competition drives student and mentor excellence

Mentoring scientific teams in a project-oriented competition, like engineers can do through the ASCE Concrete Canoe National Competition or the SAE Supermileage Competition, is rare in the microbial sciences. Mentoring a team through this experience allows scientists impart different skills than... Read More

Onward toward a Zika vaccine

On Monday, August 1, the US Centers for Disease Control and Prevention recommended that pregnant women not travel to Wynwood, a neighborhood north of downtown Miami, because health officials in Florida had found that mosquitoes there are actively transmitting Zika, a mosquito-borne virus that ca... Read More

Threat of novel swine flu viruses in pigs and humans

The wide diversity of flu in pigs across multiple continents, mostly introduced from humans, highlights the significant potential of new swine flu strains emerging, according to a study to be published in eLife. Read More

Inheritable bacterium controls Aedes mosquitoes' ability to transmit Zika

Aedes mosquitoes carrying the bacterium Wolbachia--found inside the cells of 60 percent of all insect species--are drastically less able to transmit Zika virus, say researchers at Brazil's Oswaldo Cruz Foundation (FIOCRUZ) in a study published May 4 in Cell Host & Microbe. Read More

TWiV 425: All picornaviruses, all the time

The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.


Hosts: Vincent Racaniel... Read More

Zika Virus in the USA

On this episode of Virus Watch we cover three Zika virus stories: the first human trial of a Zika virus vaccine, the first local transmission of infection in the United States, and whether the virus is a threat to participants in the 2016 Summer Olympic and Paralympic Games. Read More

Neanderthals may have been infected by diseases carried out of Africa by humans

A new study suggests that Neanderthals across Europe may well have been infected with diseases carried out of Africa by waves of anatomically modern humans, or Homo sapiens. As both were species of hominin, it would have been easier for pathogens to jump populations, say researchers. This might ... Read More

Researchers Identify Multidrug-resistant E. coli Bacteria from a New Jersey Patient

Antimicrobial resistance has been a growing concern in the health care community. But a publication by Chinese researchers in The Lancet Infectious Diseases last fall kicked things up a notch. The work found the mcr-1 gene, which confers resistance to the antibiotic colistin, in Escherichia coli... Read More

Optical tractor beam traps bacteria

Up to now, if scientists wanted to study blood cells, algae, or bacteria under the microscope, they had to mount these cells on a substrate such as a glass slide. Physicists at Bielefeld and Frankfurt Universities have developed a method that traps biological cells with a laser beam enabling the... Read More

ASM Members Deliver a Landslide Endorsement for Governance Change - Part I

Change does not come easily to most organizations, let alone to one with more than a century of history. Indeed, twice before ASM tried—and failed—to change its governance structure. This time, ASM members embraced change, realizing that ASM must become more modern and more nimble in its decisio... Read More

Researchers discover key to long-lasting malaria immunity and potential vaccine targets

Houston Methodist researchers have discovered a set of immune proteins that facilitate long-lasting immunity against malaria. In a study recently published in Immunity (online Oct. 25), researchers reported that elevated production of specific proteins regulating the immune system within 24 hour... Read More

Unlocking cryptic Strepomyces genes in the search for potential new antibiotics

Actinobacteria are the bacterial phylum responsible for production of many clinically-relevant antibacterial compounds. Streptomyces is a soil-dwelling genus of actinobacteria that produces drugs like neomycin and chloramphenicol. Despite deriving many antibiotics already from Streptomyces, coul... Read More

Low risk of dengue infection predicted for foreign visitors to Rio Olympics

In 2014, before the FIFA World Cup opened in Brazil, there were fears that many of the 600,000 foreign visitors expected for the world's largest soccer tournament would acquire dengue fever. Their numbers could reach hundreds or even thousands, according to some predictions. Read More

False impressions in predatory publishing

Imitation may be the sincerest form of flattery, but it can also be the easiest way to make a buck. That’s the primary motivation for camouflaging within an already-established brand: Sunbucks, McDowell’s, and Mountain Lightening all rely on brand recognition – of a brand that isn’t their own. W... Read More

Unknown contaminant on Blood agar

Unknown contaminant, possible Bacillus spp, seen on an old blood agar plate that had been inoculated with Strep bovis. The plate had been incubated at 37 degree's C for 24 hrs then held at room temp for a week. One colony was mucoid with a brain like appearance the other being mucoid and smoo... Read More

The six kingdoms of living things in 90 seconds

When I have to explain the organism classification to my students I usually use the one stablished by Woese in the 70s. In this classification, all living things are classified in six kingdoms, that are Eubacteria, Archeobacteria, Protista, Plantae, Fungi and Animalia. All of these groups evolve... Read More

Using a 'living antibiotic' to tackle disease

It is the first time the predatory bacterium Bdellovibrio bacteriovorus has been successfully used as an injected anti-bacterial therapy and represents an important step in the fight against drug-resistant infections, or ‘superbugs’.

Shigella infection is responsible for over 160 million illn... Read More

TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.


Hosts: Vincent Racaniel... Read More

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