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New Compound for Alcoholism Treatment

BOC Sciences-A new beta-carboline compound shows great potential for alcoholism treatment. At present, no side effects caused by the new compound have been found in the trials on rats. The compound was developed by research team from Wisconsin in Milwaukee, US. With further successful tests and ... Read More

NIH-funded study establishes genomic data set on Lassa virus

An international team of researchers has developed the largest genomic data set in the world on Lassa virus (LASV). The new genomic catalog contains nearly 200 viral genomes collected from patient samples in Sierra Leone and Nigeria, as well as field samples from the major animal reservoir, or h... Read More

'Clever adaptation' allows yeast infection fungus to evade immune system attack

Johns Hopkins Bloomberg School of Public Health researchers say they have discovered a new way that the most prevalent disease-causing fungus can thwart immune system attacks. Read More

Decontamination Exterminates Antibiotic Resistant Bacteria from Pig Farm

Washington, DC – September 4, 2015 - Decontamination protocols eradicated both methicillin-resistant Staphylococcus aureus (MRSA) and antibiotic resistant, pathogenic intestinal bacteria, the Enterobacteriaceae, from a pig farm. The research appears online September 4th in ASM’s journal Applied ... Read More

Flu vaccine reduces hospitalizations and deaths among nursing home residents

When the influenza vaccine is well matched to the prevailing strains of flu in a given season, patients in nursing homes are significantly less likely to be hospitalized or to die of pneumonia and other influenza related causes. The finding comes from a study of more than 1 million Medicare fee-... Read More

TWiV 391: Whiter reefs, fresh breath

If you have always wanted to know what coral reefs and the human oral cavity have in common, listen as guests David Pride and Forest Rohwer talk about their work on the microbiomes and viromes of these two environments, and you'll also understand why mucus is cool.


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Role of breast cell infection in flu transmission between mothers and breast-feeding ferrets

Influenza is known as an infectious respiratory disease, but a study published on October 8th in PLOS Pathogens suggests that infected cells in breast tissues could play a role in virus transmission from mothers to breast-feeding infants and vice versa using a ferret model. Read More

BacterioFiles 254 - Clostridium Consolidates Combustibles Conversion

This episode: Engineering bacteria to convert cellulose directly into useful biofuels and chemicals can be tricky!


(13.9 MB, 15.2 minutes)


Show notes: 
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Gerilizumab IL-6 is Put into Human Trial for Rheumatoid Arthritis

BOC Sciences-Recently, a biotechnology company announced that gerilizumab IL-6 as a drug for rheumatoid arthritis was under trial in healthy people. Once the safety is proved in human trial, gerilizumab will be a better alternative for rheumatoid arthritis both in effect and cost. Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

Hibernating bats mount a partial immune response against white nose fungus

White-nose syndrome (WNS), an invasive skin infection caused by the Pseudogymnoascus destructans (Pd) fungus has killed millions of bats since it was first seen in North America in 2007. A analysis of gene expression in hibernating bats infected with the destructive fungus published on October 1... Read More

TWiP 101: Is it round or is it flat?

The doctors TWiP solve the case of the Woman with White Worms, and explore the role of a secreted growth factor from a carcinogenic parasite in wound healing and angiogenesis.


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Some vaccines support evolution of more-virulent viruses

Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More

3 ANTIBIOTICS GANG UP TO KILL DEADLY STAPH

As a trio, three antibiotics that aren’t individually effective against a drug-resistant staph infection killed the deadly pathogen in test tubes and mice. Read More

Notch Inhibitors are Potential for Cancer Treatment Studies Found

BOC Sciences-Notch inhibitors like gamma-secretase inhibitors (GSIs) are found potential to slow the deterioration of various types of cancer recent studies revealed. Now further study for more accurate information about this application is undergoing, in which different cancer types are involve... Read More

Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Nobel Prize in Physiology or Medicine was Shared by Three Scientists

BOC Sciences-The three scientists who were awarded for the Noble Prize in Physiology or Medicine were all born in the 30’s of last century. They made the breakthrough both in their own scientific career and on the way of drug development for the whole humankind partly because of the spirit of pe... Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

Strategies to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Ha... Read More
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