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Immune response to flu vaccine linked to recipients' ethnic background

BOSTON -- How well a flu shot protects you from the virus can depend on your ethnic background and other inherited factors, report Dana-Farber Cancer Institute scientists. Read More


For some time, scientists have known that certain combinations of coral and algal species were more tolerant to temperature extremes than others, and therefore more likely to survive in the changing conditions predicted for the future. Read More

Guarding against immune responses limiting efficacy of antibody-based approaches to HIV

Janardan Pandey, Ph.D., an immunogeneticist specializing in immunoglobulin GM genes at the Medical University of South Carolina, helped monitor for immune responses that could limit the effectiveness of the broadly neutralizing antibody VRC01 in a phase 1 trial of that antibody in HIV-infected i... Read More

Broad, MIT scientists overcome key CRISPR-Cas9 genome editing hurdle

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on "off-target" editing errors. The refined technique addresses one of the major t... Read More

New and presumably tick-borne bacterium discovered in an Austrian fox

Adnan Hodzi from the Institute of Parasitology at the Vetmeduni Vienna is searching for pathogens transmitted by ticks. He is especially interested in wild carnivores (foxes and wolves) which could be a possible reservoir and source of infection for humans and other animals. Read More

UC San Diego scientists receive $9.5 million NIH grant to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (NIH) to establish an interdisciplinary center to define the systems biology of ... Read More

Virus Watch: Building Zika Virus

In this new video episode of Virus Watch, you'll see how the Zika virus particle is built, and how it binds to an antibody that blocks infection. All in gorgeous three dimensional views provided by recent structure studies. Read More

U of T research sheds new light on mysterious fungus that has major health consequences

Researchers at the University of Toronto examined fungi in the mucus of patients with cystic fibrosis and discovered how one particularly cunning fungal species has evolved to defend itself against neighbouring bacteria. Read More

A growing concern: why whooping cough incidence may be increasing in a highly vaccinated population

News headlines highlighting an outbreak of a vaccine-preventable disease often leave readers shaking their heads. These diseases – measles, chickenpox, whooping cough – could have been prevented if only the infected children had been vaccinated. Right? Well, in the case of whooping cough, the si... Read More

TWiP 113: Flying pigs

The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella.

Hosts: Vincent Racaniello Read More

Child with drug-resistant TB successfully treated at Johns Hopkins Children's Center

Johns Hopkins Children's Center specialists report they have successfully treated and put in remission a 2-year-old, now age 5, with a highly virulent form of tuberculosis known as XDR TB, or extensively drug-resistant TB. The case, researchers say, provides the first detailed account of a young... Read More

Diagnostic guidelines for bloodstream infections aim to shorten time to accurate therapy

One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More

TWiEVO 3: Recombination is for the birds

In episode #3 of the new science show This Week in Evolution, Nels and Vincent examine another important driver of evolution: recombination. The results of two papers in which the process is studied in finches and in yeast lead to the unexpected conclusion that recombination evolves more slowly ... Read More

New hybrid drug plugs the hole in malaria drug resistance

A combination of artemisinin and another drug (artemisinin combination therapy, ACT) is currently the best malaria treatment recommended by the World Health Organization. In early 2015, artemisinin-resistant malaria was confirmed in five countries in Southeast Asia: Cambodia, Laos, Myanmar, Thai... Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

Happy snowless winter holidays!

Beautiful bacteria. Chromobacterium violaceum, S. aureus, and S. epidermidis Read More

Young men with detectable HIV more likely to have risky sex

December 7, 2015--Young men who have sex with men and have detectable levels of HIV were more likely to report not using a condom during anal intercourse with a partner not infected with HIV, compared with virologically suppressed young men who have sex with men, according to researchers at Colu... Read More

Antibodies to dengue virus enhance infection by Zika virus

It has been speculated that the development of neurological disease and fetal abnormalities after Zika virus infection may be due to the presence of antibodies against other flaviruses that enhance disease. In support of this hypothesis, it has been shown that antibodies to dengue virus enhance... Read More

Zika virus

The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, have propelled this previously ignored virus into the limelight. What is this virus and where did it come from?
Read More

Researchers uncover essential interaction between malaria parasites and liver cells

Scientists at the Center for Infectious Disease Research recently uncovered a critical piece in the puzzle of how malaria parasites infect their host. The work, recently published in Science Magazine, reveals the details of how the malaria parasite invades its initial target organ, the liver. Wi... Read More
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