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What effect does environmental temperature have on bacterial virulence?

A recent tragic die-off of saiga antelope has scientists puzzled about what could cause such a sudden, drastic, large-scale death. Infectious disease could easily be playing a part, with Pasteurella multocida and Clostridium perfringens both possible candidates found in animal necropsies. The su... Read More

TWiV 398: Permission to be intuitive

Vincent speaks with Sandy Weller about her career and her work on the mechanisms of synthesis, maturation, cleavage and packaging of viral DNA genomes.


Host: Vincent Racaniello 


Guest: ... Read More

Urinary tract infection: How bacteria nestle in

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli. It travels along the urethra to the bladder where it triggers painful... Read More

Jan. 18 Early Registration Deadline Approaching for 2016 DOE JGI Genomics of Energy & Environment Meeting

The 11th Annual Genomics of Energy & Environment Meeting of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility, will take place March 21-24, 2016 in Walnut Creek, Calif. For information on speakers, workshops, and registration, go to http://bit.... Read More

Handprint Culture Shirt

"Everyone Needs a Little Culture" shirt @ Cabrillo College bookstore, 831-479-6209 or Niles Biological, http://www.nilesbio.com/cat499.html Read More

TWiV 393: Lovers and livers

The TWiVerati revisit possible sexual transmission of Zika virus, and reveal how a cell protein that allows hepatitis C virus replication in cell culture enhances vitamin E mediated protection against lipid peroxidation.


Hosts:  Read More

MGH team broadens utility of more compact CRISPR-Cas9 by increasing its targeting range

A team of Massachusetts General Hospital (MGH) investigators has shown that a method they developed to improve the usefulness and precision of the most common form of the gene-editing tools CRISPR-Cas9 RNA-guided nucleases can be applied to Cas9 enzymes from other bacterial sources. In a paper r... Read More

Whole-genome sequencing can help ID hospital outbreaks

Drug-resistant infections are becoming one of the scariest epidemics since the advent of antibiotic discovery. Although microbes like methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Klebsiella pneumoniae, and multidrug-resistant Pseudomonas aeruginosa are responsible for... Read More

BacterioFiles 263 - Germ Jettisoned Jellyfish Genes

This episode: Microscopic parasites of fish and worms actually came from jellyfish-like animals, after losing most of their genome!


(7.7 MB, 8.3 minutes)


Show notes: 
Read More

How immunity to RSV develops in childhood but deteriorates in adults

The leading infectious cause of severe respiratory disease in infants, respiratory syncytial virus (RSV), is also a major cause of respiratory illness in the elderly. Approved vaccines do not yet exist, and despite the development of partial immunity following infection during childhood, individ... Read More

Latest technology could help curb repeat Ebola crisis, experts say

Recent developments in surveillance technology could enable a swifter, more effective response to potentially deadly outbreaks of disease, a study has found. Read More

Less effective antimalarial therapies can help fight malaria better

Oxford University scientists have found that the more effective way to beat malaria is to use less effective drugs some of the time. Read More

Applications of Clinical Microbial Next-Generation Sequencing - American Academy of Microbiology

The American Academy of Microbiology hosted an event at the National Press Club in February 2016 to disseminate the report, "Applications of Clinical Microbial Next-Generation Sequencing".

A panel of 4 speakers discussed real world applications of NGS and findings from the report, followed b... Read More

Dispatches from ASM Microbe - Sunday

We’ve had a whirlwind of amazing talks, poster sessions, and networking sessions so far at ASM Microbe 2016. In our previous two Dispatches from ASM Microbe, we’ve covered microbiomes, for which research ranges from extremely basic (Which microbes are present? How do we quantify them?) to clinic... Read More

Vaccine against respiratory syncytial virus shows promise in early trial

Johns Hopkins Bloomberg School of Public Health researchers say a new candidate vaccine against respiratory syncytial virus (RSV) made with a weakened version of the virus shows great promise at fighting the disease, the leading cause of hospitalization for children under the age of one in the U... Read More

A microbial mystery in the Namib Desert

The Namib Desert is different than other deserts: it has an unusual geographic feature that differentiates it from most others. This desert (map, right) is where you can find ‘fairy circles,’ or circular areas absent of growth in an already plant-scarce environment. These deadened circles are su... Read More

TWiM 132 Letters

William writes:


Hi TWiMers;


It is a nice late July evening here in Berkeley - 60F/15.5C - no fog, but we have had a bit less than usual summer fog this year.


Ran across this article which is fascinating  because it falls into the category of "what... Read More

Tug of war among bacteria

At the University of Cologne, biophysicists in the lab of Professor Berenike Maier were now able to show how differential mechanical forces can lead to cell sorting in biofilms, thereby determining their architecture. In their publication in the journal eLife, the team headed by the biophysicist... Read More

Dengue: Asymptomatic people transmit the virus to mosquitoes

Scientists at the Institut Pasteur in Cambodia, the Institut Pasteur in Paris and the CNRS provided proof that people infected by dengue virus but showing no clinical symptoms can actually infect mosquitoes that bite them. It appears that these asymptomatic people - who, together with mildly sym... Read More

DRUG FROM BANANAS MAY FIGHT FLU VIRUS

Bananas contain a substance that, when changed slightly by scientists, shows promise to fight a wide range of viruses, including the flu. Read More
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