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UNC School of Medicine researchers prove HIV targets tissue macrophages

CHAPEL HILL, N.C. - Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, brain and connective tissues of the body. This dis... Read More

First case of acute myelitis in a patient infected with Zika virus

A first case of acute myelitis following infection with Zika virus has been reported for the first time by a research team from Inserm Unit 1127 Brain and Spinal Cord Institute (Inserm/CNRS/Sorbonne University) and neurologists at Pointe-à-Pitre University Hospital and the University of the Anti... Read More

New drug class offers potential new treatment for lethal bacteria

A new class of drugs has shown promise for treating the bacteria that cause legionnaires' disease, a potentially fatal lung infection. Read More

Antiviral therapy prolongs survival in immune tolerant hepatitis B patients

April 15, 2016, Barcelona, Spain: A new study, presented today at The International Liver Congress™ 2016 in Barcelona Spain, demonstrates that the use of antiviral therapy for patients in the immune tolerant phase of Hepatitis B (HBV) prolongs overall survival and reduces the risk of the most co... Read More

Lung ultrasound may be a safe substitute for chest X-ray when diagnosing pneumonia in children

Lung ultrasound has been shown to be highly effective and safe for diagnosing pneumonia in children and a potential substitute for chest X-ray, according to a study conducted at the Icahn School of Medicine at Mount Sinai. Results are currently published in the medical journal Chest. Read More

Gut microbes may play a role in Parkinson's disease

Many people with Parkinson’s disease also experience digestive symptoms (like constipation) for some time before their diagnosis. But until recently, research on the degenerative disease and how to treat it has focused on understanding how Parkinson’s works in the brain.

In a new study out th... Read More

Bacteria in Smokeless Tobacco Products May be a Health Concern

Washington, DC - August 26, 2016 - Several species of bacteria found in smokeless tobacco products have been associated with opportunistic infections, according to a paper published August 25 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. Read More

Researchers Sequence Genome from 1979 Russian Anthrax Outbreak



Bacillus anthracis had been studied by multiple countries as a potential biological weapon because of the stability of its spores and its ability to cause acute pulmonary disease. While offensive anthrax weapons development programs were halted in the United States and United Kingdom in the ... Read More

Colonies in isaw (grilled chicken intestine)

One of our class experiments include the analysis of grilled chicken intestine (isaw) under potato dextrose agar. Isaw is one of the most famous streetfood in the Philippines. And by popularity, it is also a sanctuary for yeasts and molds. The photo shows how these microorganisms formed beautifu... Read More

Tracking Bacterial Imbalance in the ICU

The human microbiome is the diverse population of microorganisms that live on and in the body. Many thrive on the skin and in the mouth, but the majority live in the intestines. Over the last decade or so, microbiologists have become increasingly aware of how a person's microbial mix likely play... Read More

Study offers clearest picture yet of how HIV defeats a cellular defender

CHAMPAIGN, Ill. -- A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say. Read More

TWiV 421: Like flies on shot

The TWiVnauts present another example of an infectious but replication incompetent vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins.


Hosts: Vincent Racaniello,&n... Read More

Newly discovered HIV genome modification may put a twist on vaccine and drug design

Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016... Read More

Thermos device quickly detects Zika for only $2

Engineers have developed a rapid, low-cost genetic test for Zika. The $2 device, about the size of a soda can, doesn’t require electricity or technical expertise and only needs a bit of saliva. Read More

Zika Sharing

Of all the scientific results that my laboratory has produced over the years, I am most satisfied by those that maximally benefit the field. In this category falls the assay for determining the titer of Zika virus in plaque forming units per milliliter.

In ‘Counting Zika Virus’ I described o... Read More

Antibiotic stewardship - a community effort

As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More

Moving to Zika Virus

I have worked on polio virus in my laboratory at Columbia University for 35 years. When that virus is eradicated--perhaps in the next few years--we will have to destroy all of our virus stocks. When that happens, I can either go home, or find another virus.

When Zika virus stepped into the w... Read More

You don't win friends with (precut) salad

Given that the holidays are right around the corner, many of us will be trying to eat healthy outside of celebratory meals, and that includes turning to salad as a healthy meal option. Salads do provide fresh nutrients, but new research in Applied and Environmental Microbiology suggests pre-cut ... Read More

Microbial Identification and Tracking: the Next Generation

How do you identify an unknown microbe? If you’ve taken an introductory microbiology lab course in the past twenty years, chances are you were assigned an unknown bacterium that you had to identify through differential media and biochemical assays. Newer techniques like qPCR are being standardiz... Read More

Environmental disturbances decrease the variability of microbial populations

A central pursuit of microbial ecology is to accurately model changes in microbial community composition in response to environmental factors. This goal requires a thorough understanding of the drivers of variability in microbial populations. However, most microbial ecology studies focus on the ... Read More
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