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A few reminiscences on Hilary Koprowski

Virologist Hilary Koprowski died on 11 April 2013 at the age of 96. His main accomplishments are nicely summarized in the New York Times, but for a more comprehensive overview of his life, I highly recommend his biography Listen to the Music by Roger Vaughan. I did not have many opportunities to... Read More

Garlic Constituent Blocks Biofilm Formation, Could Benefit Cystic Fibrosis Patients and Others

E Pluribus Unum, the de facto motto of the United States, could just as well apply to biofilm-forming bacteria. Bacterial biofilms are far more resistant than individual bacteria to the armories of antibiotics we have devised to combat them. Now Tim Holm Jakobsen and Michael Givskov of the Univ... Read More

From DNA clash, ‘double whammy’ for flies

Plant and animal cells have two genomes—in the nucleus and the mitochondria. A new study describes how a clash between the two makes fruit flies sick. Diseases from a mutation in one genome are complicated enough, but some illnesses arise from errant interactions between the DNA in the nucleus a... Read More

Study: Antibiotic stewardship program using mass spec system reduces hospital stays, costs

In peer-reviewed study, the accuracy and speed of Bruker's Biotyper analyzer integrated into a comprehensive antibiotic stewardship program reduced hospital stays by days & per patient costs substantially. A co-author of a groundbreaking study documenting reductions in patient length of stay an... Read More

Could Herpes Virus Affect Memory in Older Adults?

Older adults who harbor certain infections, such as the herpes cold sore virus, may have poorer thinking and memory abilities than their peers, a new study suggests.

Researchers found that of more than 1,600 older adults, those with signs of chronic infection with herpes simplex and certain o... Read More

Bacteria with vuvuzelas: Microbes use a channel protein as a syringe for toxins

The bacterium Photorhabdus luminescens is a constant companion of some roundworms. These worms assault insect larvae, thereby infecting them with the bacteria; the pathogens then attack the cells of their victims with a deadly cocktail of various toxins. Scientists at the Max Planck Institute of... Read More

Sequencing tracks animal-to-human transmission of bacterial pathogens

Researchers have used whole genome sequencing to reveal if drug-resistant bacteria are transmitted from animals to humans in two disease outbreaks that occurred on different farms in Denmark. The results, which are published today in EMBO Molecular Medicine, confirm animal-to-human transmission ... Read More

Harmful Algal Blooms - Microcystis ehrenbergii

You may notice a green, red or brown film on your favorite boating or swimming area in the summer. This coloring could mean that the water is affected by harmful algal blooms. Harmful algal blooms are an accumulation of tiny organisms known as algae and can release harmful toxins into the enviro... Read More

ID deadly pathogens without growing bacteria

Metagenomics has allowed researchers to reconstruct the genome sequence of a deadly Shiga-toxigenic E. coli outbreak without having to grow bacteria in the lab.

“The outbreak of Shiga-toxigenic Escherichia coli illustrated the effects of a bacterial epidemic on a wealthy, modern, industrializ... Read More

Bacteria may contribute to premature births, STDs

New research at Washington University School of Medicine in St. Louis points to a common species of bacteria as an important contributor to bacterial vaginosis, a condition linked to preterm birth and increased risk of sexually transmitted diseases.

The condition affects one in every three wo... Read More

Episode 6: Botox and Hollywood

This episode describes how the bane of sausage makers and home canners became the darling of the Hollywood set. The lethal toxin made by our friend Clostridium botulinum was put to good use paralyzing facial muscles and erasing frown lines. This video has an amazing intro sequence. Read More

Malaria: A Vector Infecting Both Apes and Humans

In 2010, a study revealed that the main agent of malaria in humans, called Plasmodium falciparum, arose from the gorilla. Today, the vector which transmitted the parasite from apes to humans has just been identified. A Franco-Gabonese research consortium has determined which species of anopheles... Read More

Intestinal Bacteria Protect Against E. Coli O157:H7

A cocktail of non-pathogenic bacteria naturally occurring in the digestive tract of healthy humans can protect against a potentially lethal E. coli infection in animal models according to research presented today at the 113th General Meeting of the American Society for Microbiology. The researc... Read More

Pioneer bacteria lay down trails that draw new recruits

Bacteria may draw other bacteria to a site of infection by laying down trails of a “molecular glue” that lead free-swimming individuals to come together and organize into colonies.

In the study, researchers were looking at how a species of bacteria called Pseudomonas aeruginosa attach and mov... Read More

Quest for Edible Malarial Vaccine Leads to Other Potential Medical Uses for Algae

Can scientists rid malaria from the Third World by simply feeding algae genetically engineered with a vaccine?

That’s the question biologists at UC San Diego sought to answer after they demonstrated last May that algae can be engineered to produce a vaccine that blocks malaria transmission. I... Read More

A Wild Bet: Can inoculating newborns with innocuous strains of bacteria save them from deadly ones?

Recently, one of Paul Cezanne’s missing paintings was rediscovered. The painting shows Paulin Paulet, a gardener on Cezanne’s family estate, looking at his poker cards. Cezanne painted Paulet as part of a series of paintings between 1890 and 1896. This particular painting is called A Card Player... Read More

NIH Scientists Develop Monkey Model to Study Novel Coronavirus Infection

National Institutes of Health (NIH) researchers have developed a model of infection in rhesus macaques that will help scientists around the world better understand how an emerging coronavirus, first identified in September 2012, affects people. The virus has so far infected at least 17 people in... Read More

Little Known Glomalin, a Key Protein in Soils

If you had heard of glomalin, you are a better person than I am. Until a couple of months ago I wasn’t aware of its existence, which is close to sinful: it happens to be a very abundant protein in the soil rhizosphere, playing a key role in the soil’s mechanical properties and as repository of s... Read More

Map of H7N9 fatalities and confirmed infections in China

Shanghai Daily has a web page set up that shows the geographic distribution of H7N9 infections and fatalities in China. There is also a news feed, information on symptoms and a photo gallery. Click "source" to view. Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


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