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TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

Early HIV treatment improves survival in some patients with newly diagnosed TB

PITTSBURGH, July 9, 2015 - Starting anti-HIV treatment within two weeks of the diagnosis of tuberculosis, or TB, improved survival among patients with both infections who had very low immune-cell counts, according to an analysis by researchers at the University of Pittsburgh Graduate School of H... Read More

New Virus Identified in Blood Supply

Washington, DC – September 22, 2015 - Scientists have discovered a new virus that can be transmitted through the blood supply. Currently, it is unclear whether the virus is harmful or not, but it is related to hepatitis C virus (HCV) and human pegivirus (HPgV), the latter of which was formerly k... Read More

BacterioFiles 217 - Fungus Fortifies Fly Food

This episode: Fruit flies have microbes that help them get more nutrition out of low-quality food!


(8.4 MB, 9.1 minutes)


Show notes: 
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Mining Marine Microbes for New Drugs

This slideshow outlines the work of WHOI scientists Tracy Mincer and Kristen Whalen in the quest to beat antibiotic resistance through bioprospecting in the ocean. Read More

Armed malaria protein found to kill cancer cells

A new type of cancer therapy based on seemingly unrelated elements of malaria and cancer is showing promise for development. Kairos Therapeutics, a Vancouver-based biotech company spun-out of The Centre for Drug Research and Development (CDRD), has partnered with VAR2 Pharmaceuticals to advance ... Read More

Sexual transmission of Ebola virus in Liberia confirmed using genomic analysis

A suspected case of sexual transmission of Ebola virus disease (EVD) in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by U.S. Army scientists in collaboration with the Liberian Institute for Biomedical Research (LIBR). Read More

New Ebola cases in single digits another week, says WHO

DAKAR, Senegal - New Ebola cases were in the single digits another week, the World Health Organization said Wednesday, showing that contact tracing efforts are yielding results.

Read More

Wasps do a gain-of-function experiment in caterpillars

Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More

Ebola’s Lessons - How the WHO Mishandled the Crisis

In a biological sense, last year’s Ebola epidemic, which struck West Africa, spilled over into the United States and Europe, and has to date led to more than 27,000 infections and more than 11,000 deaths, was a great surprise.

Local health and political leaders did not know of the presence o... Read More

ASM Live at #ICAAC / ICC - Gilead's Stribild Demonstrates Improved Safety and Efficacy Among Women Who Switched from a Multi-Pill Antiretroviral Drug Regimen

Dr. Sally Hodder, Director of the West Virginia Clinical and Translational Science Institute, will share the results from WAVES, the First International Phase 3 HIV Study to Enroll Only Women. Women are routinely underrepresented in HIV clinical trials although they account for half of the globa... Read More

ASM Live at #ICAAC / ICC - Co-contribution of rotavirus vaccines (RVs) and pneumococcal conjugate vaccines (PCVs) in reduction of pediatric hospital burden

Ron Dagan, Professor of Pediatrics and Infectious Diseases at the Pediatric Infectious Disease Unit, Soroka University Medical Center, Israel will discuss his research that showed how the introduction of both pneumococcal conjugate vaccines (PCVs) and rotavirus vaccines (RVs) led to the rapid an... Read More

TWiM #120: Snakes in trouble

Hosts: Vincent Racaniello and Elio Schaechter.


Vincent and Elio marvel in the finding that a phage tail-like struc... Read More

B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More

Killing Dormant HIV with Cancer Drug

BOC Sciences-Recently Scientists found a new way to kill the hiding and dormant Human Immunodeficiency Virus( HIV) by employing a type of cancer drug, which is proved very effective but still waiting for further trial and approval by the US FDA. Read More

High rate of Texas bugs carrying Chagas disease

A deadly parasite that causes Chagas disease is widespread in a common Texas insect, according to a new study by University of Texas at El Paso (UTEP) researchers. The finding suggests that the risk of Texans contracting the disease may be higher than previously thought. Read More

TWiV 365: Blood, feuds, and a foodborne disease

Hosts: Vincent RacanielloAlan Dove, and Kathy Spindler


For... Read More

In very ill, probiotics don't prevent 'superbugs' from colonizing intestinal tract

Compared with routine medical care, probiotics administered to critically ill patients in intensive care units showed no benefit in preventing the colonization of drug-resistant microbes in the intestinal tract, according to new research at Washington University School of Medicine in St. Louis. Read More

TWiP 100: Driving past a milestone

The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.


Hosts:  Read More

THESE YEAST CELLS SAY ‘HI’ AND OTHERS RESPOND

Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More
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