Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas pick the most appropriate treatment for bacterial infections.
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Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.
Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More
Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More
In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More
Described as the “Most Beautiful Experiment In Biology” the demonstration by Meselson and Stahl that DNA replicates semiconservatively is one of the major landmarks in the genesis of modern biology. And indeed it is most pleasing, both visually and cerebrally.
By semiconservative is meant tha... Read More
In the two days since the second U.S. Ebola patient was diagnosed, the U.S. Centers for Disease Control and Prevention (CDC) has assembled a new team to battle the threat of Ebola. This team has no steady lineup, but it will be deployed anywhere in the country that sees a new case of Ebola, CDC ... Read More
High-resolution cryo-electron microscopy has now revealed in unprecedented detail the structural changes in the bacterial ribosome which results in resistance to the antibiotic erythromycin.
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A study of biofilm formation in the model haloarchaeal species Haloferax volcanii has led to the observation of a fascinating example of coordinated social motility (and of cellular differentiation and gene transfer). Haloferax volcanii was first isolated from Dead Sea sediment in 1975, but was ... Read More
Contrary to popular belief, urine is not sterile and the bacteria in it may be associated with overactive bladder (OAB) in some women. Presenters will discuss their research ... Read More
Harvard stem cells scientists at Brigham and Women’s Hospital and MIT can now engineer cells that are more easily controlled following transplantation, potentially making cell therapies, hundreds of which are currently in clinical trials across the United States, more functional and efficient.
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On the continental margins, where the seafloor drops hundreds of meters below the water’s surface, low temperatures and high pressure lock methane inside ice crystals. Called methane hydrates, these crystals are a potential energy source, but they are also a potential source of global warming if... Read More
Dangerous new pathogens such as the Ebola virus invoke scary scenarios of deadly epidemics, but even ancient scourges such as the bubonic plague are still providing researchers with new insights on how the body responds to infections.
In a study published online Sept. 18, 2014, in the journal... Read More
Influenza infection can enhance the ability of the bacterium Streptococcus pneumoniae to cause ear and throat infections, according to research published ahead of print in the journal Infection and Immunity.
In the study, the investigators infected mice with either influenza alone, pneumococc... Read More
An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR’s Genome Institute of Singapore (GIS).
GIS’s DNA analysis technique ha... Read More
Communities in Africa and Thailand that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study in the peer-reviewed journal The Lancet Global Health.
The U.S. National Institute of Mental Health's Project Accept —... Read More
Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More
Pathogenic fungi like Candida albicans can cause oral, skin, nail and genital infections. While exposure to pathogenic fungi is generally not life-threatening, it can be deadly to immunocompromised patients with AIDS or cancer. A variety of antifungal medications, such as triazoles and polyenes,... Read More
A still somewhat unfamiliar term is floating around: the pan-genome. In 2005, Tettelin et al. coined the term along with genome analyses of eight Streptococcus agalactiae strains, and Merry introduced it to this blog, some time back already. Today, a keyword search in PubMed returns roughly 200 ... Read More
(Re-)Introducing the Pseudomonads. Despite the somewhat murky provenance of their name, pseudomonads are everything but "pseudo-" in terms of their metabolic versatility: they are bacterial omnivores, heterotrophs yet far from picky. Members of the family Pseudomonadaceae (Gammaproteobacteria) a... Read More
Some people infected with pathogens spread their germs to others while remaining symptom-free themselves. Now, investigators at the Stanford University School of Medicine believe they may know why.
When the scientists gave oral antibiotics to mice infected with Salmonella typhimurium, a bacte... Read More