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Microbial Jungles: a newly released TED-ED animation on biofilms and microbial communities

Watch our new animation on biofilms and microbial communities, with some gene transfer, cooperation and competition added for good measure! We focus on the basics of biofilm biology for a public audience and some of the ways that we benefit from the microbial communities that surround us, whethe... Read More

A role for siderophores in Klebsiella pneumoniae pathogenesis

Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.

The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More

BacterioFiles 280 - Saccharomyces Smash Small Spaces

This episode: Microbes in tight spaces grow so much they can build up pressure and burst out!


(5.5 MB, 6 minutes)


Show notes: 


News... Read More

A microbial mystery in the Namib Desert

The Namib Desert is different than other deserts: it has an unusual geographic feature that differentiates it from most others. This desert (map, right) is where you can find ‘fairy circles,’ or circular areas absent of growth in an already plant-scarce environment. These deadened circles are su... Read More

Magnetotactic bacteria remove and recover rare elements

While our human biochemical reactions are limited, our ingenuity is not, and scientists are able to exploit microbes for our benefit, such as in chemical spills. Using microbes to degrade or sequester toxic molecules is one form of bioremediation, and has many various applications. Famously, sci... Read More

TWiM 141 Letters

Tom writes:


For the article letter about microbial batteries, I think CV refers to Capacitance times Voltage, which is stored charge. In electronics, current is abbreviated I not C.


The claim in the letter got me thinking about microbial batteries and I wrote ... Read More

Study Shows How Bacteria Evolve in the Lungs of Cystic Fibrosis Patients

Washington, DC – May 24, 2016 – The bacterium Burkholderia multivorans evolves and adapts in bursts to survive in the lungs of cystic fibrosis patients, according to a study published this week in mSystems, an open access journal from the American Society for Microbiology. The work, believed to ... Read More

CMV Is a Greater Threat to Infants Than Zika, but Far Less Often Discussed

The world has been galvanized by the Zika epidemic spreading through the Americas, which has left more than two thousand infants with severe brain damage. But for pregnant women and their infants in the United States, cytomegalovirus, or CMV, is the far greater viral threat.

Every year, 20,00... Read More

Diverse fungi inhabit chronic wounds and inhibit healing

Gruesome, ghastly, grisly. These are the words that popped into my head when I googled images of diabetic foot ulcers—one of the most common chronic wounds creating a silent and costly epidemic in healthcare.

Perhaps even more shocking is the mortality rate connected to these open wounds, wh... Read More

BacterioFiles 284 - Remedies Reduce Recipient Rejection

This episode: Modifying mice's microbial communities increased mouse survival before a transplantation was rejected by their immune system!


(9.6 MB, 10.5 minutes)


Show notes: 


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TWiV 412: WO, open the borders and rig the infection

The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell.


Hosts: Vincent Ra... Read More

TWiM 140: Small town, big science

At the Hamilton, Montana Performing Arts Center, Vincent speaks with three local high school graduates and two high school teachers about how Rocky Mountain Laboratories influenced school science programs and opened up career opportunities.


Host:  Read More

Why flu is worse in eldery ?

Death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself, new research suggests.

Ninety percent of the deaths attributed to flu each year worldwide occur in people aged 65 and older. To understand why older adults are ... Read More

TWiV 429: Zika Experimental Science Team

Vincent meets with members of team ZEST at the University of Wisconsin Madison to discuss their macaque model for Zika virus pathogenesis.


Hosts: Vincent Racaniello Read More

Early-life bacterial colonizers may influence later development of asthma

This past weekend, I went to visit a friend and meet his twin toddler boys for the first time. Though both boys eagerly ran around the playground we visited, one was just slightly less active. “He has asthma,” his dad explained to me, “but his brother doesn’t.” Why would two boys with the same e... Read More

TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.


Hosts:  Read More

TWiV 421: Like flies on shot

The TWiVnauts present another example of an infectious but replication incompetent vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins.


Hosts: Vincent Racaniello,&n... Read More

Mosquito-eating fish used to fight Zika virus in Latin America

With the Zika virus spreading toward the United States, threatening pregnant mothers and the 2016 Olympics, aid workers have placed hope in a familiar fish.

In the wake of Hurricane Katrina, the Virginia-based non-profit Operation Blessing helped avert an outbreak of the West Nile virus in Ne... Read More

TWiV 425: All picornaviruses, all the time

The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.


Hosts: Vincent Racaniel... Read More

Fungus causing fatal infections in hospitalized patients has unique growth patterns

One of the important tasks of Public Health England’s Mycology Reference Laboratory is to identify any newly emerging fungal pathogens that could become a public health risk. In recent months, the lab had tracked several clusters of Candida auris infections in British hospitals. The multidrug-re... Read More
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