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New study maps hotspots of human-animal infectious diseases and emerging disease outbreaks

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

The report, wh... Read More

Which Bacteria Smell Like Tortillas, Flowers, or Delicious Browned Butter?

I’ll confess, I never quite thought about what happens when you get millions of a single kind of bacteria all together in one place and take a nice long sniff. I did not think it would ever be pleasant. I was wrong.

This level of olfactory whimsy, then, was totally new to me: Pseudomonas aeru... Read More

Bacterial Vaginosis Is Associated with Higher Risk of Female-to-Male Transmission of HIV

An investigation led by UCSF has found that the risk of female-to-male HIV transmission is increased three fold for women with bacterial vaginosis, a common disorder in which the normal balance of bacteria in the vagina is disrupted.

The new research assessed the association between bacterial... Read More

What the Germs in Your Bellybutton Say About You

At one time or another, every human goes through the rather introverted and personal experience of omphaloskepsis.

The term, better known as navel-gazing, originally described the act of self-reflection through a complete physical and mental focus on the bellybutton. The practice has been rec... Read More

Fourth of July: American Presidents and Infectious Diseases

Happy Fourth of July! In honor of this historic holiday we’ve compiled a list showing how infectious diseases and vaccines have affected the lives of our most heralded leaders – the American presidents. These concise accounts are evidence that diseases can strike anyone, anywhere at any time, an... Read More

TWiM 36: Domesticating a pathogen



Hosts: Vincent Racaniello, Read More

TWiM 36 Letters

Todd writes:

Just a quick note to say how much I enjoy TWiM, and in particular, how much I enjoyed episode 32 featuring Rosie Redfield. I don't know how you find time to do this, but I'm gl... Read More

Superbug infections dropping across US, army finds

Bloodstream infections caused by the MRSA superbug may be on the decline in communities across the U.S., according to a large study of military personnel.

Previous data from the Centers for Disease Control and Prevention show a drop in infections contracted in healthcare settings. But the tra... Read More

Rapamycin, Easter Island Drug, Shows Promise In Boosting Aging Brain, Mice Study Shows

Scientists at the University of Texas Health Science Center San Antonio are investigating a potential new drug that could improve learning and memory during aging -- thanks to Easter Island?

The drug, called rapamycin, comes from isolated bacterial products in the soil of the Polynesian islan... Read More

100 trillion good bacteria call human body home

In the search for new life, scientists have studied the depths of the ocean and the lips of steaming volcanoes. They've looked on Mars and the moons of Jupiter, and even planets beyond this solar system.

Dr. David Relman went searching inside his own mouth. On a routine dental visit in 1998, ... Read More

Tooth protection from the sea

A team of dentists and scientists from Newcastle University are developing a new product from a marine microbe to protect dentures, teeth and gums from bacteria in the mouth.

They are using an enzyme isolated from a marine bacterium Bacillus licheniformis found on the surface of seaweed which... Read More

Thoughts on the Inaugural Conference on the Microbiology of the Built Environment

". . . a guest post [to microbe.net] by David Thaler, who is one of the Sloan-funded investigators working on the microbiology of the built environment . . ."

"A few thoughts after the Inaugural meeting of Microbiology of the Built Environment Boulder.

My own opinions on these points are s... Read More

Human Microbiome Journal Club: The Pros of Probiotics

We’ve all heard the claims of probiotic yogurts and their benefits for human health, but aside from improving our belly dancing skills, what exactly are probiotic bacteria doing?

An elegant study from the Jeffrey Gordon lab explored the effects of consuming fermented milk products (FMPs) cont... Read More

BacterioFiles Micro Edition 94 - Commensals Calibrate Counterattack

This episode: Read More

A world free of 1 of the most virulent animal diseases?

One of the most economically devastating diseases in the world for those who raise cows, sheep, pigs, goats, deer and other cloven-hoofed animals is foot and mouth Disease (FMD). This incredibly contagious and fast-spreading disease causes fever, blisters on the feet and mouth (hence the name), ... Read More

Cat Litter Parasite Tied to Suicide Risk in New Moms

Mothers with IgG antibodies to Toxoplasma gondii at delivery are at risk for later self-harm or suicide, particularly if they have higher titers against the parasite, a Danish study found.

The risk of self-directed violent behavior was increased 1.53-fold (95% CI 1.27 to 1.85, Psk rose to 1.9... Read More

Searching for an Ancient Syphilis DNA in Newborns

Ancient DNA of the bacteria causing syphilis, the Treponema pallidum pallidum, can be recovered from the ancient bones of newborns. This is the conclusion reached by a study led by Universitat Autònoma de Barcelona (UAB), which was able to obtain the genetic material from the bacteria in more th... Read More

Researcher seeks to understand link between obesity, flu severity

The recent H1N1 flu pandemic was found to be particularly dangerous to obese people, and a Wayne State University researcher is looking for clues as to why.

Emily Martin, Ph.D., assistant professor of pharmacy practice in the Eugene Applebaum College of Pharmacy and Health Sciences, has begun... Read More

Oddly Microbial: 86 Million Year-Old Deep Seabed Mystery Cells

Life in a high-pressured environment with practically nothing to eat might be ok for high-fashion models, but it’s an unlikely lifestyle choice for a single cell whose usual overriding goal is to become two cells. Yet the largest living ecosystem on Earth—the deep biosphere—is comprised of micro... Read More

J&J seeks OK for first drug against resistant TB

Johnson & Johnson said Monday that it is seeking U.S. approval for the first new type of medicine to fight deadly tuberculosis in more than four decades.

The experimental drug, called bedaquiline, also would be the first medicine specifically for treating multi-drug-resistant tuberculosis. Th... Read More

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