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Resistance to last-line antibiotic also makes bacteria resistant to immune attacks

Bacterial resistance to antibiotics is bad enough, but what if drug resistance also gives bacteria the ability to fend off attacks by the immune system? In a study in mBio this week scientists identify a lose-lose situation with colistin and Acinetobacter baumannii: bacteria resistant to colisti... Read More

Update on H7N9: Should We Be Concerned?

The emergence of human infections with avian influenza viruses (H7N9 and H5N1) have raised concerns about the virus gaining the ability to spread person-to-person, potentially causing a deadly pandemic. So far the number of human cases has been limited but the mortality rates have been high. In ... Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Behind the Cover Story: Michael Pollan on Why Bacteria Aren’t the Enemy

Michael Pollan, food author, activist and journalism professor, wrote this week’s cover story about the organisms with which we share our bodies — and how we’re dependent on them. His book “Cooked: A Natural History of Transformation” came out last month. His last article for the magazine was ab... Read More

The Effects of Fracking on the Microbial Ecology of Groundwater

Hydraulic fracturing, or “fracking”, is the process of drilling and injecting fluid into the ground at a high pressure in order to fracture shale rocks to release natural gas inside. What effect does this process have on the microorganisms that naturally exist in the water in this process?

... Read More

Intestinal Bacteria Protect Against E. Coli O157:H7

A cocktail of non-pathogenic bacteria naturally occurring in the digestive tract of healthy humans can protect against a potentially lethal E. coli infection in animal models according to research presented today at the 113th General Meeting of the American Society for Microbiology. The researc... Read More

The Merlot Microbiome

Plants associated bacteria play a key role in host productivity and health. These bacteria are phylogenetically diverse and form interactions considered neutral, beneficial or detrimental. A better understanding of these interactions will have a direct impact in agriculture by promoting sustaina... Read More

New Methods for Norovirus Detection/Prevention

Norovirus is the most common cause of acute gastroenteritis in the United States. Each year, it causes about 21 million illnesses and contributes to about 70,000 hospitalizations and 800 deaths. Norovirus is also the most common cause of foodborne-disease outbreaks in the United States. Research... Read More

Food Laboratory Accuracy Remains A Concern

Food microbiology laboratories continue to submit false negative results and false positive results on a routine basis. A retrospective study of nearly 40,000 proficiency test results over the past 14 years, presented today at the 113th General Meeting of the American Society for Microbiology, ... Read More

Engineered Microbes Glow In the Dark

Scientists at the University of California, Davis have engineered a strain of photosynthetic cyanobacteria to grow without the need for light. They report their findings today at the 113th General Meeting of the American Society for Microbiology.

“In this work, we used synthetic biology appr... Read More

Bacteria Use Hydrogen, Carbon Dioxide to Produce Electricity

Researchers have engineered a strain of electricity-producing bacteria that can grow using hydrogen gas as its sole electron donor and carbon dioxide as its sole source of carbon. Researchers at the University of Massachusetts, Amherst report their findings at the 113th General Meeting of the A... Read More

Tit-for-Tat: A Bacterial Counterattack System

Microbial ecology may be a young field but it is well understood already that there is a broad spectrum of interactions between bacterial species, ranging from cooperative to competitive. In a recent paper researchers from John Mekalanos’ lab further characterized a recently discovered mechanism... Read More

The Role of the Gut Microbiome in Colon Cancer

Could the bacterial populations in your intestines predict the onset of colon cancer? Participants will discuss new research in mouse models that suggests a major shift in microbial population dynamic prior to the onset of tumors as well as the general promise microbiome research holds for the ... Read More

Good Cholesterol: Part of Innate Immunity?

Trypanosome Lytic Factor (TLF) has emerged as a novel arm of innate immunity that is only present in humans and select non-human primates. TLF was originally discovered in human blood as a minor form of High-density lipoprotein (HDL), also known as a good cholesterol, that rapidly kills the Afri... Read More

Antibiotic Compound from Wasp Venom

Antimicrobial peptides (AMPs) are part of the innate immune system that is widely distributed in nature, acting as a defense mechanism against invading microorganisms. AMPs have potent antimicrobial activity against a range of microorganisms including fungi, bacteria and viruses. In view of grow... Read More

TWiV 233: We're surrounded



Hosts: Vincent Racaniello, Rich Condit, Read More

Hunting pack of bacteria paints a tangled skein

Bacteria that glide together… make art together? This contender in the Art of Science competition run by Princeton University in New Jersey, entitled The history of gliding, depicts the squiggly gliding paths of the bacteria Myxococcus xanthus.

M. xanthus are social bacteria that move in coor... Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Now We Know Why Old Scizophrenia Medicine Works On Antibiotics-Resistant Bacteria

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci (Staphylococcus aureus).

Antibiotic-resistant bacteria is... Read More

Prominent Virologist Defends The Chinese Hybrid H5N1-H1N1 Research, Calls It ‘Good Science’

There was much written concerning the research published earlier this month in Science, where researchers from China’s Harbin Veterinary Research Institute reported creating an avian H5N1 (highly pathogenic) and pandemic 2009 H1N1 (easily transmissible) hybrid, that according to them, achieved ... Read More
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