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A Tale of Two Strategies

Bacteria are for the most part gregarious organisms, living predominantly in dense communities consisting of multiple strains. In fact, the majority of infectious bacteria occur as multi-layered structures called biofilms, many of which are composed of multiple types of bacteria. As one can imag... Read More

Early antibiotic exposure leads to lifelong metabolic disturbances in mice

Antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity, according to a new study. Moreover, the research shows t... Read More

Oddly Microbial: Selfish Genes*

Evolution is largely driven by conflict, not collaboration, according to cell evolutionist Harmit Malik at the Fred Hutchinson Cancer Research Center (FHCRC). Mammalian cells are contentious places, he explains, populated by alien and host genomic sequences fighting for dominance. "In the compet... Read More

BacterioFiles 181 - Spore-formers Smash Salmonella's Solanum Strongholds

This episode: Soil bacteria could help prevent food poisoning from bacteria in raw tomatoes!


(9.6 MB, 10.5 minutes)


Show notes: 
News item<... Read More

Vaccines can cut the spread of meningitis by nearly 40 per cent

Investigators at the University of Southampton have discovered that two new vaccines can prevent the transmission of meningitis bacteria from person to person.

The vaccines do this by reducing ‘carriage’ of the responsible bacteria in the nose and throats of the population.

Meningitis is... Read More

Dandruff-Causing Skin Fungi Discovered Unexpectedly in Deep Sea Vents, Antarctica

Until relatively recently, the fungus Malassezia was thought to have one favorite home: us. As the dominant fungus on human skin and sometimes-cause of dandruff, the yeast Malassezia was thought to live a simple if sometimes irritating domestic existence humbly mooching off the oils we exude.

... Read More

Like cling wrap, new biomaterial can coat tricky burn wounds and block out infection

Wrapping wound dressings around fingers and toes can be tricky, but for burn victims, guarding them against infection is critical. Today, scientists are reporting the development of novel, ultrathin coatings called nanosheets that can cling to the body’s most difficult-to-protect contours and ke... Read More

Demonstration of screening of Organic Acid producing Fungi.

Fungal Love......
Demonstration of screening of Organic Acid producing Fungi. Read More

Wolbachia Genome Reduction, Phage WO, and Reproductive Parasitism

Abstract:

Wolbachia are maternally transmitted endosymbionts that often alter their arthropod hosts’ biology to favor the success of infected females, and they may also serve as a speciation microbe driving reproductive isolation. Two of these host manipulations include killing males outrigh... Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

Bio-Adsorption

An example of Bio-adsorption plate assay.Observe through the margins of the colony,can see color deposits.Application in Bioremediation. Read More

It’s Funnier When You’re Right

The mystery of alcoholic fermentations was uncovered in the first half of the 19th century by Cagniard-Latour (1837) in France, and Schwann (1837) and Kützing (1837) in Germany, based on microscopic studies but not without controversy. The great German organic chemist Justus Liebig did not like ... Read More

The typhoid fever pathogen uses a cloaking mechanism to evade neutrophil neutralization

Typhoid fever is caused by systemic infection with Salmonella enterica Typhi. In contrast, infection with the closely related bacterium Salmonella enterica Thyphimurium is usually limited to the gut and causes less serious diarrheal disease. Research comparing the two pathogens reveals how S. Ty... Read More

From bite site to brain: How rabies virus hijacks and speeds up transport in nerve cells

Rabies is usually transmitted through the bite of an infected animal into muscle tissue of the new host. From there, the virus travels all the way to the brain where it multiplies and causes the usually fatal disease. A new article sheds light on how the virus hijacks the transport system in ner... Read More

Fluoribacter bozemanae expressing blue-white fluorescence under long-wave UV light.

Fluoribacter bozemanae expressing blue-white fluorescence under long-wave UV light. If you look carefully one of the steaks does not fluoresce on the right hand side of the plate. The dark colony is actually Legionella pneumophila. Read More

TWiP 76: Herpesvirus worms its way out

Vincent and Dickson discuss how infection of mice with helminths induces cytokines that reactivate a latent gamma-herpesvirus.


Hosts: Vincent Racaniello and  Read More

Self-Assembly For Me

I have the grating feeling that the subject of self-assembly of complex biological structures may not always amass the level of respect it deserves. I reckon that its importance is generally appreciated but, as topics go, it tends at times to be set aside. Yet, this is one of the most magnificen... Read More

Zombie bacteria are nothing to be afraid of

Recently identified cell-cycle controls are targets for new drugs that fight infections by shutting down division.

A cell is not a soap bubble that can simply pinch in two to reproduce. The ability to faithfully copy genetic material and distribute it equally to daughter cells is fundamental ... Read More

TWiV 300: So happy together

Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent  speaks with Dickson, Alan, Rich, and Kathy about their careers in science.


Hosts:  Read More

Zaire ebolavirus in West Africa

Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More
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