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Three wrongs make a right

Pancreatic cancer is a dreadful disease. Even in rich countries, only about 4% of those diagnosed with it are still alive after five years. In America it is the third-most-common cause of cancer deaths among women, after lung and breast cancer; among men it is fourth, after lung, prostate and co... Read More

France Probes 3 Suspected Cases of SARS-Like Virus

French health officials said Friday they are investigating three suspected cases of a deadly new respiratory virus related to SARS, in people who had close contact in the hospital with France's only confirmed case.

Beatrice Degrugillers, a spokeswoman for the regional health agency in France'... Read More

Hospitals see surge of superbug-fighting products

They sweep. They swab. They sterilize. And still the germs persist.

In U.S. hospitals, an estimated 1 in 20 patients pick up infections they didn't have when they arrived, some caused by dangerous 'superbugs' that are hard to treat.

The rise of these superbugs, along with increased pressur... Read More

Saudi Arabia reports 4 new cases of dangerous virus

Health officials reported four more cases of a dangerous new virus in Saudi Arabia on Tuesday.

Three of the patients diagnosed as having the novel coronavirus, or nCoV, are still being treated, a statement on the Saudi Health Ministry website said. The fourth has been discharged from a hospit... Read More

Taking out the defender

The in vivo interaction between a Pseudomonas aeruginosa biofilm, on a silicone implant, and the responding polymorphonuclear leukocytes.
Image: SEM imaging depicts the interaction at day 1 post insertion of the implant in the peritoneal cavity of a mouse. The leukocytes (yellow) are damaged wi... Read More

WHO says new coronavirus may be passed person to person

The World Health Organization says it appears likely that the novel coronavirus (NCoV) can be passed between people in close contact. This comes after the French health ministry confirmed a second man had contracted the virus in a possible case of human-to-human transmission. Two more people in ... Read More

Bacteria adapt and evade nanosilver’s sting

Researchers from UNSW have cautioned that more work is needed to understand how micro-organisms respond to the disinfecting properties of silver nano-particles, increasingly used in consumer goods, and for medical and environmental applications.

Although nanosilver has effective antimicrobial... Read More

The Ins and Outs of Gut Bacteria

Deep in the bowels of our, well, bowels, lurk trillions of microscopic bacteria. But don't be fooled by the big bad "B" word, intractably tied to infections and disease. In fact, these bitty bugs do us a world of good.

"There's a certain 'ick' factor associated with gut bacteria," said Lita P... Read More

Transparency Unlocked: More New Saudi Coronavirus Cases Reported Quickly

(via Wired's Superbug blog) In my last post 36 hours ago, I raised questions about Saudi Arabia’s apparent delay in reporting new cases of the novel coronavirus that has been causing low-level unease since last summer. (For the full history of that, check these posts.) So it’s only fair to say t... Read More

Bacteria help trace how alcohol binds to brain

Bacteria that grows only on rocks in the Swiss Alps has helped researchers identify how alcohol might affect key brain proteins.

“Now that we’ve identified this key brain protein and understand its structure, it’s possible to imagine developing a drug that could block the binding site,” says ... Read More

A few reminiscences on Hilary Koprowski

Virologist Hilary Koprowski died on 11 April 2013 at the age of 96. His main accomplishments are nicely summarized in the New York Times, but for a more comprehensive overview of his life, I highly recommend his biography Listen to the Music by Roger Vaughan. I did not have many opportunities to... Read More

Tricky Trichy

Trichomonas vaginalis is a protozoan parasite of the urogenital tract in men and women and causes a sexually transmitted disease, trichomoniasis, in about half of infected women. Infections are associated with pelvic inflammatory disease, adverse pregnancy outcomes, infertility, an increased inc... Read More

Study: Antibiotic stewardship program using mass spec system reduces hospital stays, costs

In peer-reviewed study, the accuracy and speed of Bruker's Biotyper analyzer integrated into a comprehensive antibiotic stewardship program reduced hospital stays by days & per patient costs substantially. A co-author of a groundbreaking study documenting reductions in patient length of stay an... Read More

Intestinal Bacteria Protect Against E. Coli O157:H7

A cocktail of non-pathogenic bacteria naturally occurring in the digestive tract of healthy humans can protect against a potentially lethal E. coli infection in animal models according to research presented today at the 113th General Meeting of the American Society for Microbiology. The researc... Read More

Malaria: A Vector Infecting Both Apes and Humans

In 2010, a study revealed that the main agent of malaria in humans, called Plasmodium falciparum, arose from the gorilla. Today, the vector which transmitted the parasite from apes to humans has just been identified. A Franco-Gabonese research consortium has determined which species of anopheles... Read More

Going viral on Science Sunday Hangout on Air

I joined Buddhini Samarasinghe and Scott Lewis on a Science Sunday Hangout on Air to talk about my career in virology: how I came to be interested in viruses, and what goes on in my laboratory. You can find hangouts and more at the ScienceSunday community.


{youtube}WpLH4gRk9gc{/youtub... Read More

Pioneer bacteria lay down trails that draw new recruits

Bacteria may draw other bacteria to a site of infection by laying down trails of a “molecular glue” that lead free-swimming individuals to come together and organize into colonies.

In the study, researchers were looking at how a species of bacteria called Pseudomonas aeruginosa attach and mov... Read More

Little Known Glomalin, a Key Protein in Soils

If you had heard of glomalin, you are a better person than I am. Until a couple of months ago I wasn’t aware of its existence, which is close to sinful: it happens to be a very abundant protein in the soil rhizosphere, playing a key role in the soil’s mechanical properties and as repository of s... Read More

Map of H7N9 fatalities and confirmed infections in China

Shanghai Daily has a web page set up that shows the geographic distribution of H7N9 infections and fatalities in China. There is also a news feed, information on symptoms and a photo gallery. Click "source" to view. Read More

Protein improves efficacy of tumor-killing enzyme

Researchers at NIAID have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio this week, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the ins... Read More
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