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Microbiomes in far-flung places: characterizing the arctic Inuit gut microbiome

The hamlet of Resolute Bay is a tiny Arctic village in the Nunavut territory of Canada with a population that hovers at or below 300. Over hundreds of perhaps even thousands of years, the traditional Inuit diet in Resolute Bay and elsewhere has been dictated by the Arctic environment. The diet i... Read More

10 Things You Need to Know about mSphereDirect

mSphereDirect is an exciting new pathway to publish your research! This groundbreaking new submission path puts you in control of getting your original research reviewed and published as soon as possible. We’ve prepared the most important things to keep in mind while preparing your manuscript s... Read More

Flaviviruses unexpectedly shut off host translation

It was a peer review request that got Alessia Ruggieri and her group at University of Heidelberg to look more closely at how Dengue virus manipulates the cellular translation and stress machineries during infection.

In a previous study, Ruggieri showed that Hepatitis C virus infection induced... Read More

Outbreak of H7N2 Flu in Cats

Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More

Bacterial communities of the female genital tract impact HIV infection risk

A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More

MdlM119: Las secuencias CRISPR: Su descubrimiento y sus futuras aplicaciones

El sistema CRISPR, su descubrimiento y posibles applicaciones:  En el episodio de hoy contamos con la presencia del Dr. Francisco Mojica de la Universidad de Alicante. 


Aprovechamos una visita suya a la Universidad de Puerto Rico para poder compartir la trayectoria de uno de... Read More

Super “Resolution”: Reflections on Microscopy in the New Year

As we shake off the holidays, 2017 brings a new opportunity for personal reflection. For many trainees, it is also a great time to focus one’s professional goals, including those related to microbiology and microscopy. In celebration of the new year, I’d like to reflect on some of the advanced m... Read More

Infant's prolonged infection reveals mutation that helps bacteria tolerate antibiotics

A life-threatening infection in an infant with leukemia led to a St. Jude Children’s Research Hospital discovery of how prolonged infection sets the stage for bacterial persistence despite antibiotic susceptibility

The quest to understand a prolonged infection in an infant being treated for l... Read More

Bacterial protein structure could aid development of new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don’t. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.

Yet one step in the process has remained a mystery because the molecu... Read More

TWiV 423: Dry, well formed, and light brown

The TWiV academia discuss induction of diarrhea by the capsid protein of an astrovirus, and association of a fungal RNA virus with white-nose syndrome of North American bats.


Hosts: Vinc... Read More

NIAID officials call for continued Zika research

Although cases of Zika virus infection appear to be decreasing, the mosquito-borne virus likely will become endemic in the Americas and continue to cause outbreaks and sporadic cases. Given the serious complications of Zika virus infection, particularly in cases of congenital infection, research... Read More

Cholera bacteria infect more effectively with a simple twist of shape

The bacteria that cause the life-threatening disease cholera may initiate infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate the intestines of their unwitting victims, according to a study led by Princeton University.

The researchers discover... Read More

First Full Genome Analysis Solves the Mystery of How Zika Got So Dangerous

The mention of Zika can strike fear in the hearts of pregnant women. With infections increasing around the world, including in the US, researchers are fighting the clock to figure out how the virus can have such horrific effects in some people. Read More

University of Miami Physicians Publish Case Study of First Locally Acquired Zika Infection

Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians with the University of Miami Health System and Miller School of Medicine published a case study January 11 in the New England Journal of Medicine, describing in detail the nation’s first locally trans... Read More

BacterioFiles 281 - Prokaryote Partners Produce Plastic

This episode: Microbes with complementary abilities help each other grow and produce useful stuff from the air!


(12 MB, 13.2 minutes)


Show notes: 


Journal Paper:

Smith MJ, Francis MB. 2016. Read More

"What will change in Clinical Microbiology Laboratories by 2050?"

If you are lucky enough to be still alive and working in 2050... How might the clinical microbiology laboratory have changed by that time? Nobody can accurately predict the future, but here are my personal thoughts... Read More

Happy Luxmas To All!

In this blog post, I reflect a bit on the ups and downs of 2016, then share some Luxmas themed art. Read More

Genetically engineered mosquitoes resist dengue fever virus

After decades of research and countless control attempts, dengue fever--a mosquito-borne viral disease--continues to infect an estimated 390 million people around the world each year. Now, researchers have reported in PLOS Neglected Tropical Diseases that the mosquitos that carry dengue virus (D... Read More

TWiV 424: FLERVergnügen

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.


Hosts:  Read More

Peanuts and Probiotics

The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More
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