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Study provides insight into aging immune systems

Compared with younger adults, the elderly are at higher risk of becoming seriously ill or dying from pneumonia. Moreover, vaccines against the disease are less effective in the elderly.

To help understand why, Loyola researchers examined two types of immune system cells, macrophages and B cel... Read More

Roundworm Could Provide New Treatment for Sepsis

Research by the University of Liverpool has found that systemic inflammation caused by sepsis can be suppressed by a protein which occurs naturally in a type of roundworm. Sepsis is a serious inflammatory condition, caused by the body over-reacting to infection. The body becomes overwhelmed by b... Read More

Research may lead to new and improved vaccines

Alum is an adjuvant (immune booster) used in many common vaccines, and Canadian researchers have now discovered how it works. The research by scientists from the University of Calgary's Faculty of Medicine is published in the March 13 online edition of Nature Medicine. The new findings will help... Read More

Study Helps Explain how Pathogenic E. coli Bacterium Causes Illness

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have shown how the O157:H7 strain of Escherichia coli causes infection and thrives by manipulating the host immune response. The bacterium secretes a protein called NleH1 t... Read More

Bacteria hijack an immune signaling system to live safely in our guts

Our immune system operates under the basic premise that "self" is different from "non-self." Its primary function lies in distinguishing between these entities, leaving the former alone while attacking the latter. Yet we now know that our guts are home to populations of bacterial cells so vast t... Read More

New way found to kill malaria parasite

A class of chemotherapy drugs designed to block signalling pathways in cancer cells also kills the parasite that causes malaria, opening up a whole new way of combating this deadly disease.

The research shows that the malaria parasite depends upon a signalling pathway present in the host, ini... Read More

Vaccine researchers warn of return of 1957 flu

Three vaccine researchers from the National Institutes of Health say that influenza A/H2N2 viruses, which caused the flu pandemic in 1957 and 1958, might return and lead to a pandemic similar to the H1N1 epidemic in 2009.

In a commentary published in this week’s issue of Nature, the scientist... Read More

Flu activity up but way behind 2009-10 season

The number of influenza-associated deaths, hospitalizations and outpatient physician visits are beginning to rise as the 2010-11 flu season progresses. But the number of cases is down considerably from the 2009-10 season marked by the arrival of the influenza A(H1N1) virus, according to a Februa... Read More

TWiV 124: Viruses that make you better

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Hosts: Vincent RacanielloDickso... Read More

TWiV 124 Letters

Norm writes:

First, I love your podcasts.

You guys are constantly grousing about the lack of research funding.

I was curious.

NIH, funding has risen every year since 2000, from $17B to the current $31B (supports 325,000 researchers)

NSF... Read More

Biophysicists Grow Pretty Bacteria In Petri Dishes To Find Antibiotics

Biophysicists are growing Petri dishes of different species of bacteria in order to develop new antibiotics. The bacteria are subjected to different temperatures and have limited food sources inside the dish. Despite these conditions, most colonies tend to communicate and reproduce. Their growth... Read More

More Negative Data for Link Between Mouse Virus and Human Disease

A new finding presented at a conference last week throws cold water on the impassioned debate about the link between a novel mouse retrovirus and prostate cancer and chronic fatigue syndrome in humans. Yet few believe it will end the controversy, which began in 2006. In an extensive sleuthing ex... Read More

Strategic Infection Prevention Measures Can Help Control Nosocomial Norovirus

Vincent Cheng, MD, of the Department of Microbiology at Queen Mary Hospital in Hong Kong, China, and colleagues conducted a study to determine if strategic infection prevention and control measures with an added test may be useful in controlling nosocomial transmission of norovirus. Their resear... Read More

Response of W.H.O. to Swine Flu Is Criticized

A panel of independent experts has harshly reviewed the World Health Organization’s handling of the 2009 epidemic of H1N1 swine flu, though it found no evidence supporting the most outlandish accusation made against the agency: that it exaggerated the alarm to help vaccine companies get rich.
... Read More

Melon Growers: Combating Cucurbit Yellow Stunting Disorder Virus

U.S. Department of Agriculture (USDA) scientists are working to give melon growers some relief from cucurbit yellow stunting disorder virus, or CYSDV.

In 2006, Agricultural Research Service (ARS) plant pathologist Bill Wintermantel with the U.S. Agricultural Research Station in Salinas, Calif... Read More

Microbes Give Mice Intestinal Fortitude

Whether a mouse lives or dies can be a matter of what bugs dwell in its gut. Microbiologists have shown that mice with the right mixture of bacteria survive a potentially fatal infection that causes diarrhea. Researchers had thought the protected mice were hardier genetically. The findings add t... Read More

Metabolomics and the Microbiome (MWV45)

In episode 45 of MicrobeWorld Video, filmed at the American Association for the Advancement of Science Meeting in Washington, D.C., Dr. Stan Maloy talks with Read More

Viruses Teach Researchers How to Protect Corn from Fungal Infection

Smut fungi are agents of disease responsible for significant crop losses worldwide. Principal investigator Dr. Thomas Smith and research associate member Dr. Dilip Shah at The Donald Danforth Plant Science Center collaborated on a project to develop a variety of corn that is highly resistant to ... Read More

Registration deadline approaching for 11th Genomic Standards Consortium Mtg at Wellcome Trust

The 11th meeting of the Genomic Standards Consortium will be meeting at the Wellcome Trust to discuss the usability of important 'omics data.
Read More


An outbreak of measles is ongoing in Geneva, Switzerland, since January 2011, in the context of a measles epidemic in neighbouring Rhône-Alpes, France. A total of 41 confirmed cases have been reported, the majority among young adults, many unaware of their non-immune status. There is no large cl... Read More
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