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Not-so-similar fate of identical twins infected with HIV-1

In 1983, identical twins boys simultaneously received a contaminated blood transfusion immediately after birth, and were subsequently diagnosed with HIV-1. Years later, one of the twins is faring very well and has a near normal immune system, while the other is in poor health and has experienced... Read More

Protozoa Could Be Controlling Your Brain

The ancient debate surrounding the existence of free will appears unresolvable, a metaphysical question that generates much heat yet little light. Common sense and volumes of psychological and neuroscientific research reveal, however, that we are less free than we think we are. Our genes, our up... Read More

Unlocking Secrets Of Plague With Stunning New Imaging Techniques

Researchers at Sandia National Laboratories have developed a super-resolution microscopy technique that is answering long-held questions about exactly how and why a cell's defenses fail against some invaders, such as plague, while successfully fending off others like E.coli. The approach is reve... Read More

Drug-Resistant Germs Lure Biotechs to Antibiotics

Optimer Pharmaceuticals Inc. (OPTR)’s Dificid is on track to lead as many as five new antibiotics onto the market over the next three years as a surge in drug- resistant germs stokes the need for new medicines.

The biotechnology industry is starting to fill a critical public-health niche bein... Read More

Baby Squid, Bugs and Microbes Launched Into Space

On 16 May, 2011, a crowd of thousands flocked to NASA’s Kennedy Space Center to witness the historic final launch of the Endeavour space shuttle.

Following days of delays and numerous technical issues, Endeavour was finally ready to ferry six astronauts to the International Space Station. Dur... Read More

CDC Release: PREVENT TB: Results of a 12-Dose, Once-Weekly Treatment of Latent Tuberculosis Infection (LTBI)

Results from one of the largest U.S. government clinical trials on tuberculosis preventive therapy to date suggest that treatment for latent tuberculosis (TB) infection – normally a difficult and lengthy regimen – may soon be easier than ever before in countries with low-to-medium incidence of T... Read More

Deadly mosquito virus spreads in Western Australia

One person has died and several others are very ill across the northern and central regions of Western Australia after contracting a virus associated with mosquito bites.

The WA Department of Health says six people have been diagnosed with Murray Valley encephalitis (MVE), a serious inflammat... Read More

Mycobacterium tuberculosis culture

This is a close-up of a Mycobacterium tuberculosis culture revealing this organism’s colonial morphology.

Note the colorless rough surface, which are typical morphologic characteristics seen in Mycobacterium tuberculosis colonial growth. Macroscopic examination of colonial growth patterns is ... Read More

Dual Neonate Vaccine Platform against HIV-1 and M. tuberculosis

Acquired immunodeficiency syndrome and tuberculosis (TB) are two of the world's most devastating diseases. The first vaccine the majority of infants born in Africa receive is Mycobacterium bovis bacillus Calmette-Guérin (BCG) as a prevention against TB. BCG protects against disseminated disease ... Read More

PCR testing for B. burgdorferi bacteria in joint fluid may confirm Lyme arthritis diagnosis

Patients with Persistent Arthritis Require More Intensive Antibiotic and DMARD Therapy

New research shows that polymerase chain reaction (PCR) testing for Borrelia burgdorferi DNA—the spirochetal bacteria transmitted by deer ticks—in joint fluid may confirm the diagnosis of Lyme arthritis, bu... Read More

TWiV 133: The HIV hideout

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Hosts: Vincent Racaniello, Read More

TWiV 133 Letters

Welkin Johnson answered John's Read More

Malaria blocks 'super-infection'

The malaria parasite can ensure it keeps a host body all to itself by preventing further malarial infections, according to international researchers.

The parasite initially reproduces in the liver and moves into the blood.

A study on mice, published in Nature Medicine, showed the parasite ... Read More

The microbiome: Viruses and pathogens in human diseases

Viruses, bacteria and other pathogens are implicated in a number of human diseases including Alzheimer's disease, epilepsy, muliple sclerosis and Parkinson's disease, ADHD, autism, bipolar disorder, depression and schizophrenia, arthritis, irritable bowel syndrome, obesity, cancers and many othe... Read More

Are C-sections fueling the obesity epidemic?

Young adults born via Cesarean section are more likely to be obese than those delivered vaginally, suggesting C-sections could be feeding the obesity epidemic, researchers have found.

But the theory is controversial. One expert cautioned that scientists are still a long way from pinning the e... Read More

Bacteria helped early animals to breathe

Mats of plant-like bacteria dramatically increase local oxygen levels in the lakes where they are found, as a result of photosynthesis. That might have given early multicellular animals the boost they needed to evolve in an ancient world where oxygen was scarce.

A study exploring this idea, p... Read More

To Study Bacteria, Scientists Blast Squid Into Space

If the final launch of the space shuttle Endeavour goes ahead as planned next week, it will be carrying an unusual cargo: baby squid.

This is not because the astronauts want a change in their menu: the squid could help us understand how "good" bacteria behave in the microgravity of space. As ... Read More

Obituary: Barry Blumberg

Although it was medicine for which he won his Nobel prize, Barry Blumberg was really an explorer. Growing up in Brooklyn, he dreamed of being Shackleton at the South Pole or Darwin on board the Beagle. His heroes were Lewis and Clark, the intrepid explorers of the new American continent, and th... Read More

The 2011 ASM General Meeting iPhone and iPod Touch App is now available in the App Store

The official app for the ASM GM 2011 is now in the iTunes store and it's free. If you are attending the meeting in New Orleans, or even if you're not, grab the app and let us know what you think. The app is for the iPhone and iPod Touch. Click the source link above to be taken to the iTunes App ... Read More

Sugar Helps Antibiotics Kill Dug-In Bacteria

Adding sugar to certain antibiotics can boost their bacteria-battling ability, according to a study published today in Nature. In particular, sugar helps the drugs wipe out persisters, bacteria that evade antibiotics by essentially going dormant only to flare up again once the danger has passed.... Read More
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