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Immune study shows how gut keeps deadly infections at bay

Treatment and prevention of life-threatening infections could be improved by research that reveals how bacteria are kept in check.

Researchers have discovered how the immune system stops bacteria in our gut from leaking into the blood stream and causing body-wide inflammation, such as sepsis.... Read More

IS IT A BIG MISTAKE TO IGNORE MINOR FLU STRAINS?

Minor variants of flu strains, which are not typically targeted in vaccines, carry a bigger viral punch than previously realized, according to a new study that examined samples from the 2009 pandemic in Hong Kong. Read More

Just a spoonful of L-arginine helps the biofilm go down

Many components of our oral hygiene regimens are meant to keep cariogenic bacteria at bay: sodium fluoride in ACT interferes with electron transport and ATP synthesis, the essential oils in Listerine have antiseptic effects, and abrasives – small, insoluble particles in toothpaste – help remove ... Read More

Trinity immunologists find new ways to beat the 'bad guys'

Vaccines are like pathogen imposters - they mimic these 'bad guys' in order to provoke a response from our immune systems, remove the invader and begin the healing process.

One of the key components in a vaccine is an adjuvant, which serves to enhance our body's immune response to vaccination... Read More

How does antimicrobial resistance spread?


How does antibiotic resistance spread?

Antibiotic resistance is the ability of bacteria to combat the action of one or more antibiotics.
Humans and animals do not become resistant to antibiotic treatments, but bacteria carried by humans and animals can.

In animal farming

Animals may ... Read More

Experimental dengue vaccine protects all recipients in virus challenge study

A clinical trial in which volunteers were infected with dengue virus six months after receiving either an experimental dengue vaccine developed by scientists from the National Institutes of Health (NIH) or a placebo injection yielded starkly contrasting results. All 21 volunteers who received th... Read More

Immune response differences might determine severity of West Nile Virus disease

While most West Nile Virus (WNV) infections in humans are asymptomatic and go unnoticed, the virus causes serious and sometimes fatal neurologic illness in some people. A study published on January 21st in PLOS Pathogens suggests that an exaggerated and abnormal immune response contributes to th... Read More

JAMA Viewpoint: Emerging Zika pandemic requires more WHO action now

WASHINGTON - The World Health Organization's Director-General should convene "urgently" a meeting of International Health Regulations' Emergency Committee to advise on the emerging Zika pandemic and galvanize global action, say two Georgetown University professors. Read More

Canadian innovation for killing mosquito eggs could help Zika fight

Toronto, Canada - With Canadian Government funding, a team of innovators from Canada and Mexico have successfully tested a low cost, environmentally-friendly way of destroying the eggs of the mosquito genus that spreads dengue, and likely spreading the Zika virus. Read More

Microbial Genomics and the Future of Food Microbiology

There’s no question that foodborne disease is a serious problem. Illnesses from contaminated foods cause over 128,000 hospitalizations and 3,000 deaths each year in the United States. The Centers for Disease Control and Prevention estimates that one in six Americans suffers a food-related illne... Read More

Typhoid toxin increases host survival and promotes asymptomatic infection

Genotoxins damage the genetic material in cells and can cause mutations and cancer. Some bacteria code for and produce genotoxins. A study published on April 7th in PLOS Pathogens reports the surprising finding that one of them, typhoid toxin, actually increases survival of the infected host and... Read More

NIH launches large clinical trials of antibody-based HIV prevention

Enrollment has begun in the first of two multinational clinical trials of an intravenously delivered investigational antibody for preventing HIV infection. Known as the AMP Studies, for antibody-mediated prevention, the trials will test whether giving people an investigational anti-HIV antibody ... Read More

And now for something completely different: optimistic news from the world of antibiotic stewardship

There’s no way to avoid the news of a growing concern for drug-resistant infections. In both life-threatening and relatively superficial infections, the ability to successfully treat microbial infections with antimicrobials is decreasing. Our only recourse is to use the drugs we have carefully w... Read More

Infant-friendly flu vaccine developed with key protein

According to the World Health Organization, influenza causes serious illness among millions of people each year, resulting in 250,000 to 500,000 deaths. Those most at risk include infants younger than six months, because they cannot be vaccinated against the disease. Now, researchers at the Univ... Read More

Natural Clay Deposit May Hold Keys to Defeating Hospital Infections

Washington, D.C.—January 26, 2016— Researchers have uncovered potent antimicrobial activity in a natural clay deposit found on the central coast of British Columbia, Canada. The research, published this week in mBio, an online open-access journal of the American Society for Microbiology, shows t... Read More

Global Pain Management Therapeutics Market to Exhibit -5.50% CAGR from 2012 to 2018 owing to Patent Expiry of Blockbuster Drugs

Chronic pain is a very common health concern in all regions across the globe. Due to the ill effects of chronic pain, there has been an increase in the demand for pain management therapeutics. The global pain management therapeutics market offers many methods or therapies of pain management such... Read More

A chromosome in every cell: PprA funcitons in chromosome segregation after Deinococcus radiodurans irradiation

Exposure to reactive oxygen species, exposure to ionizing radiation, exposure to UV light – all of these are dangerous because of their potential to alter DNA sequences. Changes in DNA can affect a protein coding sequence, potentially influencing its function, but changes in regulatory regions c... Read More

For the First Time, Researchers Identify the Secret Genetic Weapon of Clostridium difficile

Washington, DC – August 16, 2016 – A trio of researchers at the University of Texas Health Science Center, School of Public Health in Houston, have identified the location of the genes that control production of toxins that harm people infected by Clostridium difficile bacteria. The gene locus, ... Read More

Discovery of new strains of the HTLV-4 virus in hunters bitten by gorillas in Gabon

Scientists from the Institut Pasteur and the CNRS have identified two new strains of the HTLV-4 virus in two hunters who were bitten by gorillas in Gabon. These findings, published in the journal Clinical Infectious Diseases, support the notion that gorillas represent a major source of infectiou... Read More

False impressions in predatory publishing

Imitation may be the sincerest form of flattery, but it can also be the easiest way to make a buck. That’s the primary motivation for camouflaging within an already-established brand: Sunbucks, McDowell’s, and Mountain Lightening all rely on brand recognition – of a brand that isn’t their own. W... Read More
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