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The Quest for a Field Guide to the Microbes - a talk by Jonathan Eisen

A talk by Jonathan Eisen for the "Science in the River City" gathering of science teachers. Read More

Why do viruses cause disease?

Virulence, the capacity to cause disease, varies markedly among viruses. Some viruses cause lethal disease while others do not. For example, nearly all humans infected with rabies virus develop a disease of the central nervous system which ultimately leads to death. In contrast, most humans are ... Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.


Hosts: Vincent Racaniello Read More

Feeding the gut microbiota: nutrition and probiotics are key factors for digestive health

A healthy and balanced diet, as well as probiotics, have been known to be helpful in preserving gastrointestinal health for quite a long time. But it is only recently that the underlying mechanisms have become somewhat clearer. A rapidly increasing body of knowledge promises to further clarify t... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
Read More

Slaying bacteria with their own weapons

A chemist at Washington University in St. Louis is studying siderophores, iron chelating molecules released by bacteria during an infection, with the thought of using them to design personalized antibiotic therapy that would avoid the rapid evolution of resistance that plagues antibiotic drug di... Read More

New yeast species travelled the globe with a little help from the beetles

Researchers from the National Collection of Yeast Cultures (NCYC) at the Institute of Food Research (IFR) have identified a new globe-trotting yeast species that lives on tree-associated beetles. This new species demonstrates the importance of preserving biodiversity, as yeasts like this may hel... Read More

Are Microbes Winning the Antibiotic Arms Race?

Eighty-six years after the discovery of penicillin, docs are running out of antibiotics to treat serious infections like Clostridium difficile and gonorrhea, according to the Centers for Disease Control and Prevention. At the same time, the discovery of new "wonder drugs" has slowed, and microbi... Read More

Dawn attack: how plants anticipate pathogen infection

Like animals, plants are susceptible to infections from bacteria, viruses and fungi. While animals have a wide variety of immune cells and in some cases an interconnected immune system plants must rely on other methods to fight infection. A recent news bulletin from the Howard Hughes Medical Ins... Read More

Inhibiting Dengue Virus Capping Enzyme- ASM Global Video Challenge

The Geiss Lab at Colorado State University is dedicated to finding ways to prevent or inhibit dengue virus (flavivirus) infection. Dengue virus causes significant worldwide suffering and death, and there are no drugs or treatment options currently available. We are investigating the viral cappin... Read More

Ebola Patient’s Journey Shows How Global Travel Spreads Disease

The arrival in the United States of a Liberian man infected with the Ebola virus shows how easily the disease can travel and how thin the procedures are, relying heavily on the honesty of travelers and the diligence of airport workers. Some experts say that the system, given its inherent weaknes... Read More

Microbes in the Environment

Microbes are everywhere; they live in us and on us. They can't be seen with our naked eyes, thus we tent to neglect that they're there or even existed. Some microbes are harmful and some are not. However, we must learn to avoid contaminating sterile media and materials with these microbes. In th... Read More

MERS mystery: Virus found in camels

(CNN) -- Evidence is mounting against camels as leading suspects in a deadly mystery that's claimed more than 100 lives in the Middle East. The biological supervillain is the virus causing MERS-coV, short for Middle East Respiratory Syndrome, a type of coronavirus. Since the first documented cas... Read More

Thesis work on mycology for the degree of PG in Medical Microbiology.

My name is Sangeeta Khadka and i am from Nepal. I am a PG level student at St. Xavier's College. Recently, i have been doing my thesis work on mycology in Nobel Hospital and Research Centre for the degree of PG in Medical Microbiology.

This is a picture of different Candida species isolated ... Read More

Lipid Agar

Lipid Plate/Tributyrin Agar used to test for an organisms ability to produce the exoenzyme lipase which breaks down the lipids in the agar creating a clear zone around the organism. (A) Serratia marcesens, lipid hydrolysis, indicated by a zone of clearing around the growing colony, as well as th... Read More

Merry MRSA!

A little MRSA snowflake to get you in the holiday spirit. Oxacillin/Methicillin resistant Staph aureus streaked out on Spectra agar - incubated at 35C O2 for 24hrs. Follow me on instagram @stylish_streaking for more fun cultures and other images showing the beautiful side of infectious diseases!... Read More

Slime producing Staphylococcus epidermidis on Congo Red agar

Slime production by Staphylococcus epidermidis on Congo Red agar; demonstrated by black colored colonies. Slime production is one of the most important virulence factors produced by Coagulase negative Staphylococci.

The colonies of slime non-producing strains remain pink to red.
Read More

'Lonely' bacteria increase risk of antibiotic resistance

Scientists from The University of Manchester have discovered that 'lonely' microbes are more likely to mutate, resulting in higher rates of antibiotic resistance.

The study, published today in Nature Communications and jointly funded by The Wellcome Trust and Engineering and Physical Sciences... Read More

Nasal bacteria may be predictor of skin infections

Bacteria found in the nose may be a key indicator for future development of skin and soft-tissue infections in remote areas of the body, researchers say. The nose is the primary S. aureus reservoir in humans and nearly 80% of the time, an individual's colonizing strain is the same strain that ca... Read More

TWiM 79 Letters

Matthew writes:


Dear Doctors,


After listening to the second portion of TWiM 78, talking about the presence of gram-negative nosocomials around Brooklyn, I noticed a several people wearing scrubs while at lunch near a hospital in Houston, TX. Then a thought occ... Read More

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