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How our immune system targets TB

Every 18 seconds someone dies from tuberculosis - it is the world’s most deadly infectious disease.

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), has infected more than one-third of the human population with an annual death toll of approximately 1.5 million people.

... Read More

Meet Luca, the Ancestor of All Living Things

A surprisingly specific genetic portrait of the ancestor of all living things has been generated by scientists who say that the likeness sheds considerable light on the mystery of how life first emerged on Earth.

This venerable ancestor was a single-cell, bacterium-like organism. But it has a... Read More

Self-Prescribing Antibiotics is a Big Problem

Washington, DC – July 11, 2016 - Five percent of adults from a cohort of 400 people reported using antibiotics without a prescription during the previous 12 months. Twenty-five percent said they would use antibiotics without contacting a medical professional. These findings demonstrate yet anoth... Read More

E. coli: The ideal transport for next-gen vaccines?

BUFFALO, N.Y. - Most people recoil at the thought of ingesting E. coli. But what if the headline-grabbing bacteria could be used to fight disease? Read More

Unknown contaminant on Blood agar close up

Unknown contaminant, possible Bacillus spp, seen on an old blood agar plate that had been inoculated with Strep bovis. The plate had been incubated at 37 degree's C for 24 hrs then held at room temp for a week. One colony was mucoid with a brain like appearance the other being mucoid and smooth ... Read More

Drones transport microbiological samples without altering their content

Robots help sort patient samples, test clinical specimens, and analyze the results. Now a study shows that robots, in the form of drones, can help move our samples from place to place, with little effect on the analytical outcome.

Drone transport made a news splash when Amazon proposed using ... Read More

BacterioFiles 284 - Remedies Reduce Recipient Rejection

This episode: Modifying mice's microbial communities increased mouse survival before a transplantation was rejected by their immune system!


(9.6 MB, 10.5 minutes)


Show notes: 


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A quick and easy new method to detect Wolbachia bacteria in intact Aedes mosquitoes

Aedes aegypti mosquitoes transmit dengue, chikungunya, and zika viruses. A study published in PLOS NTDs reports a new technique that could make one approach to mosquito control--using Wolbachia bacteria that reduce the mosquitos' ability to transmit viral pathogens--a whole lot easier and che... Read More

New method gives scientists a better look at how HIV infects and takes over its host cells

Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have longed probed this process for insights into biology and disease, but essential details still remain out of reach.



A new approach, developed by a team of researchers led ... Read More

NIH-led effort uses implementation science to reduce mother-to-child HIV transmission

An emerging field, known as implementation science, may help reduce the nearly 150,000 instances of mother-to-child HIV transmissions that occur annually around the world, mostly in developing countries. A team of scientists and program managers, led by the National Institutes of Health, has bee... Read More

Mold contaminant on yogurt

Mold culture growing on top of a home made yogurt culture. Yogurt was made using whole milk and incubated for 8 hrs at a ~30 degree's C then refrigerated. This culture had been in the refrigerator for over 2 weeks, well past expiration for home made yogurt. The green mold had spore formation ... Read More

Antibiotic Resistance Appears to Persist in Bacteria, Even Absent Selection Pressure From Antibiotics

Washington, DC – August 1, 2016 – Plasmids are pieces of independent DNA that often carry multiple antibiotic resistance genes. Plasmids can jump from one bacterium to another, spreading that resistance. A team of French investigators now shows that bacteria that acquire plasmids containing res... Read More

Sophisticated 'mini-brains' add to evidence of Zika's toll on fetal cortex

Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its... Read More

Combination therapy cures tick-borne illness in mice

New Haven, Conn.--A novel combination therapy cures an emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease, said Yale researchers. This "radical" therapy not only clears the infection but also prevents the recurrence that often... Read More

Scraping away at the complex microbial communities that cause periodontal disease

Though both gingivitis and periodontitis are diseases of the gums, the related ailments are not simply different severities of the same disease, finds a new study published in Applied and Environmental Microbiology. Researchers confirmed this by investigating the bacterial composition of the sup... Read More

Virus y pandemias (in Spanish)

Hoy en día, en pleno siglo XXI, ¿puede un virus cambiar el mundo?, ¿puede haber una nueva pandemia mundial? En este libro explicaremos qué es un virus y cómo es la vida de un virus dentro de una célula, veremos qué es una pandemia y hablaremos sobre cómo se originan los nuevos virus de la gripe.... Read More

BacterioFiles 272 - Parasite Prevents Pollution Poisoning

This episode: Worm parasites infecting brine shrimp help them survive better in arsenic-polluted environments!


(7.9 MB, 8.6 minutes)


Show notes: 
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New study explains factors that influence the timing of infectious disease outbreaks

The delay between the time when a disease outbreak becomes possible and when it actually happens depends chiefly on how frequently infection is introduced to the population and how quickly the number of cases caused by a single individual increases, according to new research from the University ... Read More

International Team Fishes New Virus Out of the Sea of Galilee

In 2009, fish in Israel began dying in droves. And not just any fish, but the St. Peter’s fish, tilapia in the Sea of Galilee—the fish famed in the Bible for feeding the multitudes and paying the temple tax for St. Peter.

As head of the fish disease laboratory for Israel’s Ministry of Agricul... Read More

Anti-vaxx conspiracy leaders back Donald Trump, claim it's mutual

Donald Trump has a long history of promulgating anti-vaccine conspiracy theories (contrary to received wisdom, the anti-vaxx movement draws most of its support from the political right, not liberals), and the tireless leaders of the anti-vaccine movement now claim to have met with Trump and rece... Read More
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