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Unknown Fungal contaminant on Mueller Hinton agar #2

Unknown fungal contaminant seen on Mueller Hinton agar after several months at refrigerated temperature. Colony had a white non-spore forming apron around the edges with green spore formation seen on the inner layer/center. Read More

First-in-man trial of MERS vaccine begins at Walter Reed Army Institute of Research

SILVER SPRING, Md. - The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East Respiratory Syndrome (MERS). Read More

Unknow FUngal contaminant on Lipid agar

Unknown fungal contaminant seen on Lipid agar after several months at refrigerated temperatures. Image taken using transmitted light to highlight the concentric rings of the colony. COlor was a dark brownish green. Read More

Scientists identify effective and novel mechanisms to block chikungunya virus

December 10, 2015, San Francisco, CA--Scientists looking at the antiviral mechanisms of two previously identified human monoclonal antibodies have found they potently inhibit chikungunya virus (CHIKV) at multiple stages of infection. Read More

UMMS scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant professor in microbiology & physiological systems, reveals new lea... Read More

Getting closer to understanding Zika virus, one genome at a time

Several papers published in Genome Announcements recently describe the sequences of new Zika virus isolates. Scientists have known the genomic sequence of at least one Zika virus isolate since 2007, but continue to publish newly isolated strains. What is the importance of these additional sequen... Read More

Ferreting out an improved Ebola animal model

We’ve previously covered the importance of diagnostics in disease control and treatment. This is vital to controlling disease progression and transmission, but epidemiology studies can’t always show how a disease progresses or transmits. This is where scientists need a well-characterized animal ... Read More

Cockroach Caca Contains Chemical Messages Made by Microbes

Microbes play a huge role in our nutrition, our immunity, maybe even our mental health. But we aren’t the only ones that rely on these armies of resident bacteria. "Baby cockroaches, the ones that just emerge from the egg, don't have any gut bacteria." Coby Schal, an entomologist and chemical ec... Read More

Study offers clearest picture yet of how HIV defeats a cellular defender

CHAMPAIGN, Ill. -- A new study offers the first atomic-scale view of an interaction between the HIV capsid - the protein coat that shepherds HIV into the nucleus of human cells - and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say. Read More

Flu vaccine shows promise for reducing risk of influenza-associated atrial fibrillation

Philadelphia, PA, February 2, 2016 - Influenza is significantly associated with an increased risk of new-onset atrial fibrillation, which could be reduced through influenza vaccination, according to new findings reported HeartRhythm. Read More

Gut damage identified as cause of vaccine failure, malnutrition

It has been estimated that if every nutritional measure known to be helpful were applied to every child in the world, global malnutrition would be decreased by only a third. New research from the University of Virginia School of Medicine, the University of Vermont and the International Centre fo... Read More

Cyclin' out of gear: Malaria parasites grinding to a halt

Scientists from The University of Nottingham have uncovered the role of cyclin -- the protein molecule that drives the growth of malaria within mosquitoes. Read More

War and peace in the human gut: Probing the microbiome

Human well being often flourishes under conditions of cooperation with others and flounders during periods of external conflict and strife.

According to Athena Aktipis, a researcher at Arizona State University's Biodesign Institute, microbes within the body--collectively known as the microbi... Read More

Skin infections rife among high school wrestlers, say CU Anschutz researchers

DENVER (Feb. 3, 2016) - The first national survey of skin infections among high school athletes has found that wrestlers have the highest number of infections, with football players coming in a distant second, according to researchers at the University of Colorado Anschutz Medical Campus. Read More

Lung ultrasound may be a safe substitute for chest X-ray when diagnosing pneumonia in children

Lung ultrasound has been shown to be highly effective and safe for diagnosing pneumonia in children and a potential substitute for chest X-ray, according to a study conducted at the Icahn School of Medicine at Mount Sinai. Results are currently published in the medical journal Chest. Read More

TWiP 114: Plant potions perturb Plasmodium

The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.


Hosts: Vincent Racaniello Read More

Young Inventors Work On Secret Proteins To Thwart Antibiotic-Resistant Bacteria

Three young inventors and students at Stanford University are working to develop proteins that fight antibiotic resistant bacteria. They are optimistic they have found something that works. The proteins the team is developing attack "something that's essential to bacterial survival". But they wo... Read More

NIH scientists draw evidence-based blueprint for HIV treatment and prevention

For many years, clinicians debated the best time to start antiretroviral therapy (ART) for HIV infection, with some worrying that the risks of treatment in terms of drug toxicities could outweigh the benefits of controlling the virus. In a new commentary, scientists from the National Institute o... Read More

Listeria: Hypervirulent strains with cerebral and placental tropism

Researchers from the Institut Pasteur, Inserm, CNRS and Paris Descartes - Sorbonne Paris Cité University recently published a large-scale study in Nature Genetics based on almost 7,000 strains of Listeria monocytogenes -- the bacterium responsible for human listeriosis, a severe foodborne infect... Read More

Virus Watch: Zika Edition

Virus Watch is a new weekly video series that explores the amazing world of viruses. This week: the latest research on Zika virus, including finding virus in Brazilian monkeys, dengue antibodies helping Zika virus infection, and brain organoids to study how Zika virus causes microcephaly. Read More
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