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Additives to Boost Vaccine Responses Not Sufficient to Protect Obese Mice From Influenza

Washington, DC – August 2, 2016 – Adjuvants – ingredients added to vaccinations for influenza and other viruses to help boost their effectiveness – can increase a host’s immune response but not enough to protect the obese against the ill effects of the flu, according to a mouse study published t... Read More

Self-Prescribing Antibiotics is a Big Problem

Washington, DC – July 11, 2016 - Five percent of adults from a cohort of 400 people reported using antibiotics without a prescription during the previous 12 months. Twenty-five percent said they would use antibiotics without contacting a medical professional. These findings demonstrate yet anoth... Read More

International Team Fishes New Virus Out of the Sea of Galilee

In 2009, fish in Israel began dying in droves. And not just any fish, but the St. Peter’s fish, tilapia in the Sea of Galilee—the fish famed in the Bible for feeding the multitudes and paying the temple tax for St. Peter.

As head of the fish disease laboratory for Israel’s Ministry of Agricul... Read More

“Spillover: Zika, Ebola & Beyond” Film Screening and Discussion at National Museum of Natural History, Nov 15, 6:30 PM ET

Over the last half century, a number of diseases have spilled over from animals to humans with increasing frequency. What's behind the rise in spillover diseases? What can we do to stop them? Spillover — Zika, Ebola & Beyond is a harrowing documentary that follows scientists into the world's ... Read More

Anti-vaxx conspiracy leaders back Donald Trump, claim it's mutual

Donald Trump has a long history of promulgating anti-vaccine conspiracy theories (contrary to received wisdom, the anti-vaxx movement draws most of its support from the political right, not liberals), and the tireless leaders of the anti-vaccine movement now claim to have met with Trump and rece... Read More

NIH-led effort uses implementation science to reduce mother-to-child HIV transmission

An emerging field, known as implementation science, may help reduce the nearly 150,000 instances of mother-to-child HIV transmissions that occur annually around the world, mostly in developing countries. A team of scientists and program managers, led by the National Institutes of Health, has bee... Read More

Sophisticated 'mini-brains' add to evidence of Zika's toll on fetal cortex

Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its... Read More

New method gives scientists a better look at how HIV infects and takes over its host cells

Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have longed probed this process for insights into biology and disease, but essential details still remain out of reach.



A new approach, developed by a team of researchers led ... Read More

BacterioFiles 287 - Producing Potent Pathogen Prophylaxes

This episode: Polymer-coated bacteria make really good vaccines!


(9.2 MB, 10 minutes)


Show notes: 


News item



Jou... Read More

Antibiotic Resistance Appears to Persist in Bacteria, Even Absent Selection Pressure From Antibiotics

Washington, DC – August 1, 2016 – Plasmids are pieces of independent DNA that often carry multiple antibiotic resistance genes. Plasmids can jump from one bacterium to another, spreading that resistance. A team of French investigators now shows that bacteria that acquire plasmids containing res... Read More

What are gut bacteria doing in critically ill lungs? New discovery could change ICU care

No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients.

Today, scientists are reporting that they found gut bacteria in the deepest r... Read More

'FishTaco' sorts out who is doing what in your microbiome

A growing body of evidence indicates that the trillions of microbes that live on and inside our bodies affect our health. Collectively, these resident microbes form our microbiome.

In a new paper appearing in the journal Cell Host & Microbe, researchers at the University of Washington report ... Read More

Microbiome: A Cultural Revolution

The Microbiome is enjoying some much deserved attention as people are starting to realize that we are not alone in our body.....and its a good thing! Culture was done using a large TSA plate, Serratia marcescens (red), Staphylococcus epidermidis (white, arms and legs), and an unknown environmen... Read More

Getting the hologenome concept right

Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or l... Read More

Combination therapy cures tick-borne illness in mice

New Haven, Conn.--A novel combination therapy cures an emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease, said Yale researchers. This "radical" therapy not only clears the infection but also prevents the recurrence that often... Read More

Fitness landscapes for microbial pathogens in agricultural systems

How is it that we are we able to devote so little of our personal time and energy to producing or acquiring the healthy, safe food that we consume multiple times every day? A large part of the reason we seldom worry about agricultural output is that most of us benefit enormously from modernized,... Read More

Earliest Signs Of Animal Life May Be From Microbes

Evidence suggests that microbes existed on Earth as far back as 3.7 billion years ago, a billion years after the planet formed. Animal remains, however, don't appear in the fossil record until 600 million years ago during the Ediacaran period, though there are indirect signs that animal life may... Read More

In case you missed it: best of mBiosphere 2016

From archaeal viruses to zoonotic diseases, the breadth of microbiology stories covered on mBiosphere in 2016 was impressive. Here are some of the best posts on mBiosphere from throughout this past year:
Read More

Microscopic technique to observe antibiotics live in action

A new microscopic technique is enabling scientists to observe the antibiotic daptomycine live in action. This marks an exciting first, because even though doctors have been prescribing this antibiotic for over a decade, its precise mechanisms have remained unclear.

First, the scientists tagg... Read More

Why odds are against a large Zika outbreak in the US

Is the United States at risk for a large-scale outbreak of Zika or other mosquito-borne disease? While climate conditions in the U.S. are increasingly favorable to mosquitos, socioeconomic factors such as access to clean water and air conditioning make large-scale outbreaks unlikely, according t... Read More
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