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Bacterium and Fungus Team Up to Cause Virulent Tooth Decay in Toddlers

Early childhood caries, a highly aggressive and painful form of tooth decay that frequently occurs in preschool children, especially from backgrounds of poverty, may result from a nefarious partnership between a bacterium and a fungus, according to a paper published ahead of print in the journal... Read More

E.coli on MacConkey Agar (Mac)

Streak plate isolation of E. coli on MacConkey Agar grown for 24 hrs at 37 degrees. E. coli demonstrates strong lactose fermentation indicated by the bright pink halo, bile precipitant around the colonies, and pink colony growth. Read More

TWiP 62 letters

 


Blaine writes:


Hi Twippies,


I saw today in the New York Times that a hookworm vaccine will be tested in Gabon. I found this very intriguing as your discussions of parasitic worms have rarely included the possibility of vaccines. Can you please c... Read More

Lab-on-a-Chip Tracks Down 'Most Wanted' Microbe

A diagnostic tool that’s about the size of a credit card has identified a highly prized gut microbe.

The microbe contains interesting genetic sequences, but it has proven challenging to culture in the lab.

Researchers used the device, called SlipChip, to isolate microbes from a patient’s g... Read More

New chip lets scientists listen in on bacteria

Researchers at Columbia University are turning that optics-based imaging approach on its head, instead developing a chip based on integrated circuit technology that lets them not only electrochemically image bacteria, but listen in on them as well.

Click on 'source' to read more. Read More

Endospore Stain Bacillus cereus

B. cereus was grown on urea agar for 6 days at 37 degrees C to induce spore formation.
The endospore stain was done using malachite green as the primary stain and safranin as counter the stain. Malachite green was applied to the smear and set over a steaming water bath for 10 min (stain was no... Read More

The Strange Connection Between Germs and Sherlock Holmes

Sherlock Holmes was as much a scientist as a detective. Maybe that’s because his creator, Arthur Conan Doyle, was influenced by a detective of science: Robert Koch, a German doctor who helped prove the existence of germs. In his new book, The Remedy, Thomas Goetz traces connections between the t... Read More

Bacteria-Eating Viruses 'Magic Bullets in the War On Superbugs'

A specialist team of scientists from the University of Leicester has isolated viruses that eat bacteria -- called phages -- to specifically target the highly infectious hospital superbug Clostridium difficile (C. diff).

Now an exciting new collaboration between the University of Leicester, th... Read More

Researchers Discover Possible New Target To Attack Flu Virus

Scientists at The University of Texas at Austin have discovered that a protein produced by the influenza A virus helps it outwit one of our body's natural defense mechanisms. That makes the protein a potentially good target for antiviral drugs directed against the influenza A virus.

Better an... Read More

TWiV 294: Smallpox and anthrax and flu, oh my!

The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members.


Hosts:  Read More

The truth behind the '5-Second Rule': When in doubt, throw it out

The burger patty that slides off the plate, the ice cream treat that plops on the picnic table, the hot dog that rolls off the grill – conventional wisdom has it that you have five seconds to pick it up before it is contaminated.

Fact or folklore?

“A dropped item is immediately contaminate... Read More

Swirling and whirling: the movement of spherical bacteria

Research on bacterial movement tends to focus on the rod-shaped bacteria. With the aid of small waving flagella, each bacterial cell can push itself in the direction it wishes to go. They can also move in groups, forming large swarms that ripple and slide their way across Petri dishes. Spherical... Read More

UGA researchers uncover how bacteria helps create clouds

When a clear sunny day turns into clouds, people used it to explain their grave mood without taking into consideration how clouds can affect global warming in the atmosphere. But University of Georgia marine researchers have discovered the process of an anti-greenhouse gas known as DMSP (dimethy... Read More

Virus-induced fever might change bacteria from commensal to pathogen

Neisseria meningitidis may cause septicemia (bacteria in the blood) and meningitis (infection of the membrane surrounding the brain), but the bacterium colonizes the nasopharynx in 10-20% of the human population without causing disease. Although understanding how the bacterium changes from a com... Read More

Target 2 forms of iron to control cystic fibrosis lung infection

The bacterium Pseudomonas aeruginosa needs iron to establish and maintain a biofilm in the lungs of cystic fibrosis patients, and therapies have been proposed to deprive the bacteria of this necessary element. However, these techniques may not work, according to a new study published in mBio®, t... Read More

Cubist & Cambridge Science Festival Launch "Germ Challenge" Science Contest

LEXINGTON, Mass. & CAMBRIDGE, Mass.--(BUSINESS WIRE)--February 13, 2014--
Cambridge Science Festival and Cubist Pharmaceuticals, Inc. (NASDAQ: CBST) today launched the 2014 "Germ Challenge," a contest designed to engage young people in science by inviting them to create educational and creativ... Read More

How U.S. Hospitals Are Planning To Stop The Deadly MERS Virus

In the past month, Middle East Respiratory syndrome has morphed from a little-known disease in the Arabian Peninsula to a major global health concern, with more than 300 cases in Saudi Arabia in April, 54 of them fatal.

Two cases have been reported in the U.S. as well — one in Indiana and one... Read More

Multiple protocol breaches behind anthrax exposure at U.S. federal labs

The safety breach at a government lab that may have exposed 84 workers to live anthrax centered on a pivotal lapse in procedure: researchers working with the bacteria waited 24 hours to be sure they had killed the pathogens, half the time required by a new scientific protocol.

The lab designe... Read More

What Makes Good Bacteria Go Bad? It's Not Them, It's You

Imagine a friend of a friend brings his family to stay with you — his family of tiny survivalists. For weeks or months you all live quietly side by side with no problems. You share meals. Your kids play together.

Then one day you get sick — maybe felled by a bad cold or the flu. Suddenly cert... Read More

Bacteria 'could be a cause of preterm births'

New research from the US has found a link between preterm births where the water sac around the baby breaks prematurely, and bacteria near where the walls of the sac are thinner.

The researchers, including Amy P. Murtha, associate professor of obstetrics and gynecology at Duke University Scho... Read More

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