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Skin bacterium releases enzyme that may protect against damage and disease

The study - from Lund University in Sweden and published in the journal Scientific Reports - investigates a skin bacterium called Propionibacterium acnes. Senior author Dr. Rolf Lood, from Lund's Department of Clinical Sciences, explains:

"The name originates from the fact that the bacterium ... Read More

TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.


Hosts:  Read More

Researchers hope hybrid compounds can sensitize and inhibit malaria parasites in one blow

Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More

Virus Watch: Zika Edition

Virus Watch is a new weekly video series that explores the amazing world of viruses. This week: the latest research on Zika virus, including finding virus in Brazilian monkeys, dengue antibodies helping Zika virus infection, and brain organoids to study how Zika virus causes microcephaly. Read More

An achilles heel for Clostridium difficile infections?

Clostridium difficile is a dangerous superbug. Infections with this bacterium can cause life-threatening diarrhea, and they are most likely to affect the elderly or people with health problems who spend a lot of time in hospitals (where C. difficile flourishes). The Centers for Disease Control a... Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More

UMMS scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant professor in microbiology & physiological systems, reveals new lea... Read More

Bacteria take 'RNA mug shots' of threatening viruses

Scientists from The University of Texas at Austin, the Stanford University School of Medicine and two other institutions have discovered that bacteria have a system that can recognize and disrupt dangerous viruses using a newly identified mechanism involving ribonucleic acid (RNA). It is similar... Read More

TWiV 412: WO, open the borders and rig the infection

The TWiVome reveal the first eukaryotic genes found in a bacteriophage of Wolbachia, and how DNA tumor virus oncogenes antagonize sensing of cytoplasmic DNA by the cell.


Hosts: Vincent Ra... Read More

SOME FROGS ARE EVOLVING TO SURVIVE A KILLER FUNGUS

As reported in a new study in the the journal Proceedings of Royal Society B: Biological Sciences, scientists have taken a step toward identifying the genetic mechanisms that makes some lowland leopard frogs in Arizona resistant to Batrachochrytrium dendrobatridis (Bd) infections that cause the ... Read More

Wealth of unsuspected new microbes expands tree of life

Researchers at the University of California, Berkeley, who have discovered more than 1,000 new types of bacteria and Archaea over the past 15 years lurking in Earth's nooks and crannies, have dramatically rejiggered the tree to account for these microscopic new life forms. Read More

Student Thoughts On The First Day of Microbiology Class

I teach Microbiology at the University of Puget Sound every fall semester. The swiftly changing field of microbiology has depth and breath...and I was interested to learn what my students thought of the topic at the beginning of the first day of class. We will revisit this subject at the end o... Read More

Bid to beat baby chest infection boosted by immune study

Babies at risk of a serious lung infection could be helped by a therapy based on the body's natural immune defences. Read More

Moving beyond metagenomics to find the next pandemic virus

I was asked to write a commentary for the Proceedings of the National Academy of Sciences to accompany an article entitled SARS-like WIV1-CoV poised for human emergence. I’d like to explain why I wrote it and why I spent the last five paragraphs railing against regulating gain-of-function experi... Read More

Public health concern as data reveals high prevalence of hepatitis B among refugees in Germany

April 16, 2016, Barcelona, Spain: A new study presented today demonstrates the potential challenge posed to public health systems across Europe as a result of the prevalence of Hepatitis B among new refugee populations. The study was presented at The International Liver Congress™ 2016 in Barcelo... Read More

Getting closer to understanding Zika virus, one genome at a time

Several papers published in Genome Announcements recently describe the sequences of new Zika virus isolates. Scientists have known the genomic sequence of at least one Zika virus isolate since 2007, but continue to publish newly isolated strains. What is the importance of these additional sequen... Read More

Antimicrobial in Common Toothpaste Doesn't Impact Gut, Oral Microbiome

Washington, DC - May 18, 2016 - Personal hygiene products such as soaps and toothpastes that contain the antibiotic triclosan do not have a major influence on microbial communities or endocrine function, according to a small, randomized trial. The study findings were published online May 18th in... Read More

Curcumin may help overcome drug-resistant tuberculosis

New research indicates that curcumin--a substance in turmeric that is best known as one of the main components of curry powder--may help fight drug-resistant tuberculosis. In Asia, turmeric is used to treat many health conditions and it has anti-inflammatory, antioxidant, and perhaps even antica... Read More

Zika virus plaque assay

Several weeks ago we perfected a plaque assay for Zika virus, based on our existing assays for enteroviruses. Shown is a photograph of two plates stained with crystal virolet with clearly delineated plaques. The cells are Vero and the Zika virus strain is MR766, an African isolate. Anyone intere... Read More

UNC School of Medicine researchers prove HIV targets tissue macrophages

CHAPEL HILL, N.C. - Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, brain and connective tissues of the body. This dis... Read More
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