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An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More

Stopping Candida in its tracks

Scientists are one step closer to understanding how a normally harmless fungus changes to become a deadly infectious agent. Read More

Prion trials and tribulations: Finding the right tools and experimental models

Prions are fascinating, enigmatic, and might teach us not only about rare prion diseases like Creutzfeld-Jakob disease, mad cow disease, or scrapie, but also about other more common neurodgenerative diseases. Two studies published on July 2nd in PLOS Pathogens report progress with novel tools an... Read More

TWiM #121: A plague of pathogens

Filmed live at ASM Biodefense 2016 with special guests: Rebekah Kading and Wyndham Lathem.


Fr... Read More

TWiV 370: Ten out of 15

Hosts: Vincent RacanielloAlan Dove, and Kathy Spindler


<... Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

TWiM #120: Snakes in trouble

Hosts: Vincent Racaniello and Elio Schaechter.


Vincent and Elio marvel in the finding that a phage tail-like struc... Read More

Agar Double Helix

Inspired by the current Agar Art Contest and the gorgeous red of a recently isolated Serratia, I thought I'd try out my first bacteria "sketch." Using Serratia, Citrobacter, and an E. coli on Hektoen Agar I whipped up this goey DNA double helix! Read More

One in four hepatitis C patients denied initial approval for drug treatment

New Haven, Conn. -- Nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection, according to a Yale School of Medicine study. Read More

Your Gut Bacteria May Be Controlling Your Appetite

Hear that little voice in your head telling you to skip a second slice of pumpkin pie? It might be coming not from your conscience, but from the masses of bacteria in your stomach.

Experiments in mice and rats suggest that certain microbes living in your body as part of the gut microbiome hav... Read More

Brown University to help Ghana build HIV, TB research capacity

PROVIDENCE, R.I. [Brown University] -- Tuberculosis is the leading cause of death among HIV-positive Ghanaians, with one study blaming TB for 57 percent of HIV-related deaths in the mid-sized West-African nation. To tackle the problem, a partnership between Brown University and the University of... Read More

Pitt researchers to monitor resistance to HIV drugs in Africa

PITTSBURGH, Aug. 3, 2015 - Infectious diseases researchers from the University of Pittsburgh School of Medicine are leading a five-year, $5 million initiative to monitor drug resistance during the rollout of HIV prevention drugs in sub-Saharan Africa. Read More

ASM Live at #ICAAC / ICC - Bordetella parapertussis Outbreak in Southeastern Minnesota in 2014

Vytas Karalius, Medical Student at Mayo Medical School, Mayo Clinic, and Dr. Robin Patel, director of the Infectious Diseases Research Laboratory at Mayo Clinic discuss an outbreak of Bordetella parapertussis in Southeastern Minnesota and examine the efficacy of the vaccine against different spe... Read More

HIV testing among older adults is declining, despite CDC recommendation

Researchers led by the UCLA Fielding School of Public Health examined HIV testing trends among adults ages 50 through 64 both before and after 2006, when the Centers for Disease Control and Prevention (CDC) recommended that most doctors automatically screen all patients for HIV regardless of whe... Read More

TWiP 100: Driving past a milestone

The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.


Hosts:  Read More

The Mechanism of Aging May Be Found By Scientists

BOC Sciences-Anti-aging has long been a research and study subject, but few breakthrough has been made since no original reason was found for this normal body change with age increasing. Recently scientists from TSRI may find the underlying reason for aging diseases. Read More

Chickenpox vaccination does increase shingles cases, but mainly in young adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. Read More

New understanding of genetic susceptibility to infections by Candida and Mycobacterium

The discovery of bi-allelic mutations in RORC in patients with candidiasis and mycobacteriosis revealed the pivotal role of RORC in mucocutaneous immunity to Candida and in systemic immunity to Mycobacterium in humans. Read More

TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

Dengue protein modulates human enzyme: Fuel for replication

Dengue is a mosquito-borne tropical disease currently endemic in more than 10 countries. According to the World Health Organization, 390 million people are infected by dengue every year. Read More

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