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BacterioFiles 276 - Single-cell Slime School

This episode: Individual slime molds show the ability to learn about their environment!


(8.8 MB, 9.6 minutes)


Show notes: 


News item... Read More

BacterioFiles 279 - Hijacker Heightened Hyphal Heterogeneity

This episode: Fungi control their cell's growth and division with a protein from a virus, unlike all other kinds of eukaryote!


(8.9 MB, 9.75 minutes)


Show notes: 


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Congenital Zika Syndrome

Data from several clinical studies in Brazil establish a strong link between infection of pregnant women with Zika virus and a variety of birth defects collectively called congenital Zika syndrome.

In the latest study conducted in Rio de Janeiro, the authors enrolled 88 pregnant women who had... Read More

A role for siderophores in Klebsiella pneumoniae pathogenesis

Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.

The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More

Mayo researchers identify new Borrelia species that causes Lyme disease

Rochester, Minn. -- Mayo Clinic researchers, in collaboration with the Centers for Disease Control and Prevention (CDC) and health officials from Minnesota, North Dakota and Wisconsin, have discovered a new bacterial species that causes Lyme disease in people. The new species has been provisiona... Read More

Early-life bacterial colonizers may influence later development of asthma

This past weekend, I went to visit a friend and meet his twin toddler boys for the first time. Though both boys eagerly ran around the playground we visited, one was just slightly less active. “He has asthma,” his dad explained to me, “but his brother doesn’t.” Why would two boys with the same e... Read More

TWiV 415: Ebola pipettors and the philosopher's clone

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.


Hosts:  Read More

Fungus causing fatal infections in hospitalized patients has unique growth patterns

One of the important tasks of Public Health England’s Mycology Reference Laboratory is to identify any newly emerging fungal pathogens that could become a public health risk. In recent months, the lab had tracked several clusters of Candida auris infections in British hospitals. The multidrug-re... Read More

TWiM #136: Diderms and then monoderms

The TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.


Hosts: Vincent Racaniello, El... Read More

Diverse fungi inhabit chronic wounds and inhibit healing

Gruesome, ghastly, grisly. These are the words that popped into my head when I googled images of diabetic foot ulcers—one of the most common chronic wounds creating a silent and costly epidemic in healthcare.

Perhaps even more shocking is the mortality rate connected to these open wounds, wh... Read More

CDC confirms Zika virus does cause microcephaly

For the first time, US disease experts have agreed that the mosquito-borne Zika virus does indeed cause babies to be born with abnormally small heads — a condition known as microcephaly. Until now, the two conditions were linked — but experts didn’t know for sure if Zika caused the brain-damaged... Read More

BacterioFiles 275 - Building Bacterial Batteries

This episode: Scientists build a battery out of microbes and electrodes that can store and release electricity repeatedly!


(7.5 MB, 8.1 minutes)


Show notes: 


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Yale study suggests immune response to flu causes death in older people, not the virus

New Haven, Conn.-- A new Yale-led study suggests that death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself. The insight could lead to novel strategies for combating flu in the most vulnerable patients, said the resear... Read More

Why flu is worse in eldery ?

Death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself, new research suggests.

Ninety percent of the deaths attributed to flu each year worldwide occur in people aged 65 and older. To understand why older adults are ... Read More

TWiM 135 Letters

Reed writes:


Dear Vincent, Elio, Michael, and Michelle,


I've just recently finished TWiM number 133 and wanted to comment about the use of the term "secondary metabolite" throughout the episode and often in the primary literature. Michael pointed out that a se... Read More

Mosquito-eating fish used to fight Zika virus in Latin America

With the Zika virus spreading toward the United States, threatening pregnant mothers and the 2016 Olympics, aid workers have placed hope in a familiar fish.

In the wake of Hurricane Katrina, the Virginia-based non-profit Operation Blessing helped avert an outbreak of the West Nile virus in Ne... Read More

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.


Hosts:  Read More

Dispatches from ASM Microbe: Entire series

Things have been quiet on mBiosphere lately. We've been busy updating from ASM Microbe, covering some of the fascinating research presented there. The first Microbe meeting, which combines the former general meeting and ICAAC, was a whirlwind of poster presentations, lectures, seminars, book sig... Read More

TWiV 402: The plight of the bumblebee

Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV.


Hosts: Vincent Racaniello Read More

Improving the quality of dairy products

Bitter tasting yogurt or cheese may not make it to your refrigerator, but it is produced and the result of pesky bacteria. The microbial composition of raw milk impacts the quality, shelf life, and safety of processed milk and other dairy products. Controlling the quality of these products is tr... Read More
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