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Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Freshmen, Extra Credit, and Different Ways of Learning

In this blog post, I show how students in my freshman "introduction to cell and molecular biology" course used "creativity"-based approaches to better understand concepts in the course---as they prepare for their upcoming final exam. I believe that this kind of approach truly helps with student... Read More

Mothers' Day, Marcus Aurelius, and Microbiology.

On this Mothers' Day, I reflect on the role my late mother had on my own decision to become a scientist. We all owe are mothers a great deal, and not just for the mitochondria! So hurray for mothers everywhere! Read More

Keeping Viral Load Low

Over the past 30 years, the combined efforts of scientists and clinicians have delivered remarkable successes in HIV therapeutics. Since 1987, the FDA has approved more than 30 antiviral drugs, including 12 HIV protease inhibitors and one integrase inhibitor. These drugs stop ~99% of viral repli... Read More

Genome Sequencing Provides Unprecedented Insight Into Causes of Pneumococcal Disease

A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population following the introduction of a vaccine. The study follows how th... Read More

Resistance to last-line antibiotic also makes bacteria resistant to immune attacks

Bacterial resistance to antibiotics is bad enough, but what if drug resistance also gives bacteria the ability to fend off attacks by the immune system? In a study in mBio this week scientists identify a lose-lose situation with colistin and Acinetobacter baumannii: bacteria resistant to colisti... Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Catch-and-Release

Another major goal of synthetic biology is to engineer unnatural molecules and compounds into systems and tools that mimic those found in biology. For instance, Joanna Aizenberg and her laboratory have pioneered using self-assembling synthetic nanofibers to generate capture-and-release devices t... Read More

Resistance to Visceral Leishmaniasis: New Mechanisms Involved

Researchers from CNRS, Université Toulouse III -- Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 and mannose receptors participate in the protection against the parasite... Read More

TWiV 233: We're surrounded



Hosts: Vincent Racaniello, Rich Condit, Read More

New Methods for Norovirus Detection/Prevention

Norovirus is the most common cause of acute gastroenteritis in the United States. Each year, it causes about 21 million illnesses and contributes to about 70,000 hospitalizations and 800 deaths. Norovirus is also the most common cause of foodborne-disease outbreaks in the United States. Research... Read More

Behind the Cover Story: Michael Pollan on Why Bacteria Aren’t the Enemy

Michael Pollan, food author, activist and journalism professor, wrote this week’s cover story about the organisms with which we share our bodies — and how we’re dependent on them. His book “Cooked: A Natural History of Transformation” came out last month. His last article for the magazine was ab... Read More

Food Laboratory Accuracy Remains A Concern

Food microbiology laboratories continue to submit false negative results and false positive results on a routine basis. A retrospective study of nearly 40,000 proficiency test results over the past 14 years, presented today at the 113th General Meeting of the American Society for Microbiology, ... Read More

Biosensor That Detects Antibiotic Resistance Brings Us One Step Closer to Fighting Superbugs

On May 8th JoVE will publish research that demonstrates how a biosensor can detect antibiotic resistance in bacteria. This new technology is a preliminary step in identifying and fighting superbugs, a major public health concern that has led to more deaths than AIDS in the United States in recen... Read More

Study: Handbags May Have More Bacteria Than A Toilet Seat

Many ladies love their handbags and will spend a lot of money for the latest and greatest, but a new study says what is inside those bags may be covered in germs worse than what you’ll find in the bathroom.

As CBS 2′s Cindy Hsu reported Wednesday, the study said your purse may, in fact, have ... Read More

Thymus Teaches Immune Cells to Ignore Vital Gut Bacteria

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say.

When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be ... Read More

Clawed frogs spread deadly amphibian fungus

The African clawed frog, a species used around the world for biomedical research, is spreading an amphibian-killing fungus when they are released into the wild. In a new study, researchers provide the first evidence that the frogs in California harbor a fungal infection that is decimating amphib... Read More

The Microbiome of the Sky: Role for Microbes in Cloud Formation?

Whether the microorganisms routinely inhabit the upper troposphere -- perhaps living on carbon compounds also found there -- or whether they were simply lofted there from the Earth's surface isn't yet known. Airborne microbes are of interest to atmospheric scientists, because they could play a r... Read More

To Defeat Bacteria, Researchers Think Like Bacteria

A new approach to treating antibiotic-resistant infections has been developed by University of Wollongong (UOW) and University of New South Wales’ (UNSW) researchers who have patented the new technology and entered into commercialization discussions with two French pharmaceutical companies.

A... Read More

Now We Know Why Old Scizophrenia Medicine Works On Antibiotics-Resistant Bacteria

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci (Staphylococcus aureus).

Antibiotic-resistant bacteria is... Read More
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